Medical cannabis: Mechanisms of action and therapeutic targets
Introduction: In recent years, multiple publications underscored many beneficial properties associated with medical marihuana. Its current applications encompass pain relief, multiple sclerosis, the treatment of anxiety disorders, Dravet syndrome and other. It can potentially extent to the treatmen...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Kazimierz Wielki University
2024-02-01
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| Series: | Journal of Education, Health and Sport |
| Subjects: | |
| Online Access: | https://apcz.umk.pl/JEHS/article/view/48137 |
| _version_ | 1797303539425345536 |
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| author | Klaudia Kowalczyk Patryk Lasek Natalia Trąbka Paulina Binkowska Gabriela Demidowicz Nina Lasota Maciej Smerdzyński Katarzyna Łach Kinga Ściurka Kinga Panuciak |
| author_facet | Klaudia Kowalczyk Patryk Lasek Natalia Trąbka Paulina Binkowska Gabriela Demidowicz Nina Lasota Maciej Smerdzyński Katarzyna Łach Kinga Ściurka Kinga Panuciak |
| author_sort | Klaudia Kowalczyk |
| collection | DOAJ |
| description |
Introduction: In recent years, multiple publications underscored many beneficial properties associated with medical marihuana. Its current applications encompass pain relief, multiple sclerosis, the treatment of anxiety disorders, Dravet syndrome and other. It can potentially extent to the treatment of patients with fibromyalgia or in people with diabetic complications. The expansive potential of medical cannabis in the prevention and treatment of many diseases is seen in its complex and multidirectional mechanisms of action. Medical marihuana has impact on cannabinoid receptors, and it exerts effects through many other molecular targets.
Aim of the study: This review seeks present mechanisms of action of medical marihuana and explore its potential therapeutic targets.
Materials and methods: A comprehensive review of literature available in the PubMed and Google Scholar databases was performed, using the following keywords: "medical marihuana", "medical cannabis", "medical marihuana mechanism of action", "therapeutic targets of medical marihuana", "endocannabinoid system", “medical marihuana in pain treatment”, “medical marihuana amygdala body”, “medical marihuana serotonin receptors”.
Conclusions: Medical marihuana emerges as a promising candidate in the treatment of many diseases and common condition. However, further research is imperative to ascertain the effects of the drug and transform it into an effective medication which maximizes benefits and minimalizes side effects.
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| first_indexed | 2024-03-07T23:55:12Z |
| format | Article |
| id | doaj.art-bdb4308da39c42919ac3d96140df409a |
| institution | Directory Open Access Journal |
| issn | 2391-8306 |
| language | English |
| last_indexed | 2024-03-07T23:55:12Z |
| publishDate | 2024-02-01 |
| publisher | Kazimierz Wielki University |
| record_format | Article |
| series | Journal of Education, Health and Sport |
| spelling | doaj.art-bdb4308da39c42919ac3d96140df409a2024-02-18T11:53:03ZengKazimierz Wielki UniversityJournal of Education, Health and Sport2391-83062024-02-015810.12775/JEHS.2024.58.013Medical cannabis: Mechanisms of action and therapeutic targetsKlaudia Kowalczyk0Patryk Lasek1Natalia Trąbka2Paulina Binkowska3Gabriela Demidowicz4Nina Lasota5Maciej Smerdzyński6Katarzyna Łach7Kinga Ściurka8Kinga Panuciak9Pharmacy “Centrum Zdrowia”, Bankowa 5/U1 street, 72-010 Police, PolandDoctoral School, Medical University of Lublin, 7 Chodźki St., 20-093 Lublin, PolandMedical Center ANAMED 21-100 Lubartów, Kolejowa 5, PolandPharmacy “Centrum Zdrowia” Grunwaldzka 21, 72-600 ŚwinoujścieJoanna Bartoszewska M.D. 21-143 Abramów, Szkolna 10, Poland Private Health Center “Medicus”, Dmowskiego 37, 97-300 Piotrków TrybunalskiCounty Health Center in Brzeziny sp. z o. o. st. Marii Skłodowskiej-Curie 6, 95-006 Brzeziny24-300 Opole Lubelskie, Partyzancka 17a, PolandUniversity Hospital in Krakow, 31-501 Kraków, Mikołaja Kopernika 36, PolandIndependent Public Clinical Hospital No. 4 in Lublin Jaczewskiego 8, 20-954 Lublin Introduction: In recent years, multiple publications underscored many beneficial properties associated with medical marihuana. Its current applications encompass pain relief, multiple sclerosis, the treatment of anxiety disorders, Dravet syndrome and other. It can potentially extent to the treatment of patients with fibromyalgia or in people with diabetic complications. The expansive potential of medical cannabis in the prevention and treatment of many diseases is seen in its complex and multidirectional mechanisms of action. Medical marihuana has impact on cannabinoid receptors, and it exerts effects through many other molecular targets. Aim of the study: This review seeks present mechanisms of action of medical marihuana and explore its potential therapeutic targets. Materials and methods: A comprehensive review of literature available in the PubMed and Google Scholar databases was performed, using the following keywords: "medical marihuana", "medical cannabis", "medical marihuana mechanism of action", "therapeutic targets of medical marihuana", "endocannabinoid system", “medical marihuana in pain treatment”, “medical marihuana amygdala body”, “medical marihuana serotonin receptors”. Conclusions: Medical marihuana emerges as a promising candidate in the treatment of many diseases and common condition. However, further research is imperative to ascertain the effects of the drug and transform it into an effective medication which maximizes benefits and minimalizes side effects. https://apcz.umk.pl/JEHS/article/view/48137medical marihuanamedical cannabismedical marihuana mechanism of actiontherapeutic targets of medical marihuanaendocannabinoid systemmedical marihuana in pain treatment |
| spellingShingle | Klaudia Kowalczyk Patryk Lasek Natalia Trąbka Paulina Binkowska Gabriela Demidowicz Nina Lasota Maciej Smerdzyński Katarzyna Łach Kinga Ściurka Kinga Panuciak Medical cannabis: Mechanisms of action and therapeutic targets Journal of Education, Health and Sport medical marihuana medical cannabis medical marihuana mechanism of action therapeutic targets of medical marihuana endocannabinoid system medical marihuana in pain treatment |
| title | Medical cannabis: Mechanisms of action and therapeutic targets |
| title_full | Medical cannabis: Mechanisms of action and therapeutic targets |
| title_fullStr | Medical cannabis: Mechanisms of action and therapeutic targets |
| title_full_unstemmed | Medical cannabis: Mechanisms of action and therapeutic targets |
| title_short | Medical cannabis: Mechanisms of action and therapeutic targets |
| title_sort | medical cannabis mechanisms of action and therapeutic targets |
| topic | medical marihuana medical cannabis medical marihuana mechanism of action therapeutic targets of medical marihuana endocannabinoid system medical marihuana in pain treatment |
| url | https://apcz.umk.pl/JEHS/article/view/48137 |
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