<i>O</i>-Aminoalkyl-<i>O</i>-Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells

<i>O</i>-Aminoalkyl-<i>O</i>-Trimethyl-2,3-Dehydrosilybins: Synthesis and In Vitro Effects Towards Prostate Cancer Cells

As part of our ongoing silybin project, this study aims to introduce a basic nitrogen-containing group to 7-OH of 3,5,20-<i>O</i>-trimethyl-2,3-dehydrosilybin or 3-OH of 5,7,20-<i>O</i>-trimethyl-2,3-dehydrosilybin via an appropriate linker for in vitro evaluation as potentia...

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Bibliographic Details
Main Authors: Bao Vue, Sheng Zhang, Andre Vignau, Guanglin Chen, Xiaojie Zhang, William Diaz, Qiang Zhang, Shilong Zheng, Guangdi Wang, Qiao-Hong Chen
Format: Article
Language:English
Published: MDPI AG 2018-11-01
Series:Molecules
Subjects:
silybin
prostate cancer
2,3-dehydrosilybin
cell proliferation
cell apoptosis
Online Access:https://www.mdpi.com/1420-3049/23/12/3142

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