Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review
Kayexalate (sodium polystyrene sulfonate) is a cation-exchange resin used to treat patients with hyperkalemia. Concomitant administration of kayexalate and sorbitol may induce gastrointestinal injury, which is potentially lethal. However, this well-documented complication is often underrecognized bo...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2011-04-01
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| Series: | Kaohsiung Journal of Medical Sciences |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1607551X10000458 |
| _version_ | 1798046206871470080 |
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| author | Yueh-Hung Chou Hsin-Yi Wang Min-Shu Hsieh 周岳弘 王馨儀 謝明書 |
| author_facet | Yueh-Hung Chou Hsin-Yi Wang Min-Shu Hsieh 周岳弘 王馨儀 謝明書 |
| author_sort | Yueh-Hung Chou |
| collection | DOAJ |
| description | Kayexalate (sodium polystyrene sulfonate) is a cation-exchange resin used to treat patients with hyperkalemia. Concomitant administration of kayexalate and sorbitol may induce gastrointestinal injury, which is potentially lethal. However, this well-documented complication is often underrecognized both clinically and pathologically. We propose a typical case along with colonoscopic photos and microscopic pictures. Additionally, we also present a review of the literature on this rare drug-induced side effect. |
| first_indexed | 2024-04-11T23:33:46Z |
| format | Article |
| id | doaj.art-bdb6648122be4a90b7277c3a67d1726a |
| institution | Directory Open Access Journal |
| issn | 1607-551X |
| language | English |
| last_indexed | 2024-04-11T23:33:46Z |
| publishDate | 2011-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Kaohsiung Journal of Medical Sciences |
| spelling | doaj.art-bdb6648122be4a90b7277c3a67d1726a2022-12-22T03:57:02ZengWileyKaohsiung Journal of Medical Sciences1607-551X2011-04-0127415515810.1016/j.kjms.2010.12.010Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature reviewYueh-Hung Chou0Hsin-Yi Wang1Min-Shu Hsieh2周岳弘3王馨儀4謝明書5Department of Anatomical Pathology, Far Eastern Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pathology, National Taiwan University Hospital Yun-Lin Branch, TaiwanDepartment of Anatomical Pathology, Far Eastern Memorial Hospital, Taipei, TaiwanDepartment of Internal Medicine, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pathology, National Taiwan University Hospital Yun-Lin Branch, TaiwanKayexalate (sodium polystyrene sulfonate) is a cation-exchange resin used to treat patients with hyperkalemia. Concomitant administration of kayexalate and sorbitol may induce gastrointestinal injury, which is potentially lethal. However, this well-documented complication is often underrecognized both clinically and pathologically. We propose a typical case along with colonoscopic photos and microscopic pictures. Additionally, we also present a review of the literature on this rare drug-induced side effect.http://www.sciencedirect.com/science/article/pii/S1607551X10000458Gastrointestinal injuryIschemic enterocolitisKayexalateSodium polystyrene sulfonateSorbitol |
| spellingShingle | Yueh-Hung Chou Hsin-Yi Wang Min-Shu Hsieh 周岳弘 王馨儀 謝明書 Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review Kaohsiung Journal of Medical Sciences Gastrointestinal injury Ischemic enterocolitis Kayexalate Sodium polystyrene sulfonate Sorbitol |
| title | Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review |
| title_full | Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review |
| title_fullStr | Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review |
| title_full_unstemmed | Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review |
| title_short | Colonic necrosis in a young patient receiving oral kayexalate in sorbitol: Case report and literature review |
| title_sort | colonic necrosis in a young patient receiving oral kayexalate in sorbitol case report and literature review |
| topic | Gastrointestinal injury Ischemic enterocolitis Kayexalate Sodium polystyrene sulfonate Sorbitol |
| url | http://www.sciencedirect.com/science/article/pii/S1607551X10000458 |
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