Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries
Abstract Background Many studies have demonstrated adverse effects of exposure to aircraft noise on health. Possible biological pathways for these effects include hormonal disturbances. Few studies deal with aircraft noise effects on saliva cortisol in adults, and results are inconsistent. Objective...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2019-11-01
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| Series: | Environmental Health |
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| Online Access: | http://link.springer.com/article/10.1186/s12940-019-0540-0 |
| _version_ | 1818858760243773440 |
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| author | Clémence Baudin Marie Lefèvre Jenny Selander Wolfgang Babisch Ennio Cadum Marie-Christine Carlier Patricia Champelovier Konstantina Dimakopoulou Danny Huithuijs Jacques Lambert Bernard Laumon Göran Pershagen Töres Theorell Venetia Velonaki Anna Hansell Anne-Sophie Evrard |
| author_facet | Clémence Baudin Marie Lefèvre Jenny Selander Wolfgang Babisch Ennio Cadum Marie-Christine Carlier Patricia Champelovier Konstantina Dimakopoulou Danny Huithuijs Jacques Lambert Bernard Laumon Göran Pershagen Töres Theorell Venetia Velonaki Anna Hansell Anne-Sophie Evrard |
| author_sort | Clémence Baudin |
| collection | DOAJ |
| description | Abstract Background Many studies have demonstrated adverse effects of exposure to aircraft noise on health. Possible biological pathways for these effects include hormonal disturbances. Few studies deal with aircraft noise effects on saliva cortisol in adults, and results are inconsistent. Objective We aimed to assess the effects of aircraft noise exposure on saliva cortisol levels and its variation in people living near airports. Methods This study focused on the 1300 residents included in the HYENA and DEBATS cross-sectional studies, with complete information on cortisol sampling. All the participants followed a similar procedure aiming to collect both a morning and an evening saliva cortisol samples. Socioeconomic and lifestyle information were obtained during a face-to-face interview. Outdoor aircraft noise exposure was estimated for each participant’s home address. Associations between aircraft noise exposure and cortisol outcomes were investigated a priori for male and female separately, using linear regression models adjusted for relevant confounders. Different approaches were used to characterize cortisol levels, such as morning and evening cortisol concentrations and the absolute and relative variations between morning and evening levels. Results Statistically significant increases of evening cortisol levels were shown in women with a 10-dB(A) increase in aircraft noise exposure in terms of LAeq, 16h (exp(β) = 1.08; CI95% = 1.00–1.16), Lden (exp(β) = 1.09; CI95% = 1.01–1.18), Lnight (exp(β) = 1.11; CI95% = 1.02–1.20). A statistically significant association was also found in women between a 10-dB(A) increase in terms of Lnight and the absolute variation per hour (exp(β) = 0.90; CI95% = 0.80–1.00). Statistically significant decreases in relative variation per hour were also evidenced in women, with stronger effects with the Lnight (exp(β) = 0.89; CI95% = 0.83–0.96) than with other noise indicators. The morning cortisol levels were unchanged whatever noise exposure indicator considered. There was no statistically significant association between aircraft noise exposure and cortisol outcomes in men. Conclusions The results of the present study show statistically significant associations between aircraft noise exposure and evening cortisol levels and related flattening in the (absolute and relative) variations per hour in women. Further biological research is needed to deepen knowledge of the pathway between noise exposure and disturbed hormonal regulation, and specially the difference in effects between genders. |
| first_indexed | 2024-12-19T09:01:24Z |
| format | Article |
| id | doaj.art-bdb7f4ab3e1f4727b9d30a382b57740e |
| institution | Directory Open Access Journal |
| issn | 1476-069X |
| language | English |
| last_indexed | 2024-12-19T09:01:24Z |
| publishDate | 2019-11-01 |
| publisher | BMC |
| record_format | Article |
| series | Environmental Health |
| spelling | doaj.art-bdb7f4ab3e1f4727b9d30a382b57740e2022-12-21T20:28:28ZengBMCEnvironmental Health1476-069X2019-11-0118111210.1186/s12940-019-0540-0Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countriesClémence Baudin0Marie Lefèvre1Jenny Selander2Wolfgang Babisch3Ennio Cadum4Marie-Christine Carlier5Patricia Champelovier6Konstantina Dimakopoulou7Danny Huithuijs8Jacques Lambert9Bernard Laumon10Göran Pershagen11Töres Theorell12Venetia Velonaki13Anna Hansell14Anne-Sophie Evrard15Univ Lyon, Université Claude Bernard Lyon1, ifsttar, umrestte, umr t_9405, Cité des MobilitésUniv Lyon, Université Claude Bernard Lyon1, ifsttar, umrestte, umr t_9405, Cité des MobilitésInstitute of Environmental Medicine, Karolinska InstituteFederal Environment AgencyEnvironmental Health Unit, Agency for Health ProtectionHospices Civils de Lyon GH Sud CBAPS Laboratoire de BiochimieIFSTTAR, Planning, Mobilities and Environment Department, Dynamics of Mobility Changes TeamDepartment of Hygiene, Epidemiology and Medical Statistics Faculty of Medicine, National and Kapodistrian, University of AthensNational Institute of Public Health and Environmental ProtectionCurrently retiredIFSTTAR, Transport, Health and Safety DepartmentInstitute of Environmental Medicine, Karolinska InstituteStress Research Institute, Faculty of Social Sciences, Stockholm UniversityNurses School, National and Kapodistrian, University of AthensCentre for Environmental Health and Sustainability, University of LeicesterUniv Lyon, Université Claude Bernard Lyon1, ifsttar, umrestte, umr t_9405, Cité des MobilitésAbstract Background Many studies have demonstrated adverse effects of exposure to aircraft noise on health. Possible biological pathways for these effects include hormonal disturbances. Few studies deal with aircraft noise effects on saliva cortisol in adults, and results are inconsistent. Objective We aimed to assess the effects of aircraft noise exposure on saliva cortisol levels and its variation in people living near airports. Methods This study focused on the 1300 residents included in the HYENA and DEBATS cross-sectional studies, with complete information on cortisol sampling. All the participants followed a similar procedure aiming to collect both a morning and an evening saliva cortisol samples. Socioeconomic and lifestyle information were obtained during a face-to-face interview. Outdoor aircraft noise exposure was estimated for each participant’s home address. Associations between aircraft noise exposure and cortisol outcomes were investigated a priori for male and female separately, using linear regression models adjusted for relevant confounders. Different approaches were used to characterize cortisol levels, such as morning and evening cortisol concentrations and the absolute and relative variations between morning and evening levels. Results Statistically significant increases of evening cortisol levels were shown in women with a 10-dB(A) increase in aircraft noise exposure in terms of LAeq, 16h (exp(β) = 1.08; CI95% = 1.00–1.16), Lden (exp(β) = 1.09; CI95% = 1.01–1.18), Lnight (exp(β) = 1.11; CI95% = 1.02–1.20). A statistically significant association was also found in women between a 10-dB(A) increase in terms of Lnight and the absolute variation per hour (exp(β) = 0.90; CI95% = 0.80–1.00). Statistically significant decreases in relative variation per hour were also evidenced in women, with stronger effects with the Lnight (exp(β) = 0.89; CI95% = 0.83–0.96) than with other noise indicators. The morning cortisol levels were unchanged whatever noise exposure indicator considered. There was no statistically significant association between aircraft noise exposure and cortisol outcomes in men. Conclusions The results of the present study show statistically significant associations between aircraft noise exposure and evening cortisol levels and related flattening in the (absolute and relative) variations per hour in women. Further biological research is needed to deepen knowledge of the pathway between noise exposure and disturbed hormonal regulation, and specially the difference in effects between genders.http://link.springer.com/article/10.1186/s12940-019-0540-0EpidemiologyAircraft noise exposureSaliva cortisol |
| spellingShingle | Clémence Baudin Marie Lefèvre Jenny Selander Wolfgang Babisch Ennio Cadum Marie-Christine Carlier Patricia Champelovier Konstantina Dimakopoulou Danny Huithuijs Jacques Lambert Bernard Laumon Göran Pershagen Töres Theorell Venetia Velonaki Anna Hansell Anne-Sophie Evrard Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries Environmental Health Epidemiology Aircraft noise exposure Saliva cortisol |
| title | Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries |
| title_full | Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries |
| title_fullStr | Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries |
| title_full_unstemmed | Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries |
| title_short | Saliva cortisol in relation to aircraft noise exposure: pooled-analysis results from seven European countries |
| title_sort | saliva cortisol in relation to aircraft noise exposure pooled analysis results from seven european countries |
| topic | Epidemiology Aircraft noise exposure Saliva cortisol |
| url | http://link.springer.com/article/10.1186/s12940-019-0540-0 |
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