Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia

Introduction The lack of local side effect profiles for vaccines could hinder vaccination uptake. Since all COVID-19 vaccines are brand-new medications, it is crucial to keep track of any safety related concern. Objective This study is aimed to investigate post-vaccination side effects of COVID-19 v...

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Main Authors: Ebrahim Abdela Siraj MSc, Ashagrachew Tewabe Yayehrad MSc, Zewdu Yilma MSc, Tamyalew Getahun MSc, Mequannent Sharew Melaku MSc, Gizachew Kassahun Bizuneh MSc, Zemene Demelash Kifle MSc, Dawit Kumilachew Yimenu MSc
Format: Article
Language:English
Published: SAGE Publishing 2023-04-01
Series:SAGE Open Nursing
Online Access:https://doi.org/10.1177/23779608231172358
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author Ebrahim Abdela Siraj MSc
Ashagrachew Tewabe Yayehrad MSc
Zewdu Yilma MSc
Tamyalew Getahun MSc
Mequannent Sharew Melaku MSc
Gizachew Kassahun Bizuneh MSc
Zemene Demelash Kifle MSc
Dawit Kumilachew Yimenu MSc
author_facet Ebrahim Abdela Siraj MSc
Ashagrachew Tewabe Yayehrad MSc
Zewdu Yilma MSc
Tamyalew Getahun MSc
Mequannent Sharew Melaku MSc
Gizachew Kassahun Bizuneh MSc
Zemene Demelash Kifle MSc
Dawit Kumilachew Yimenu MSc
author_sort Ebrahim Abdela Siraj MSc
collection DOAJ
description Introduction The lack of local side effect profiles for vaccines could hinder vaccination uptake. Since all COVID-19 vaccines are brand-new medications, it is crucial to keep track of any safety related concern. Objective This study is aimed to investigate post-vaccination side effects of COVID-19 vaccines and associated factors in Bahir Dar city. Method An institutional-based cross-sectional study was conducted among vaccinated clients. A simple random and a systematic random sampling method were used to select the health facilities and the participants, respectively. Bi-variable and multivariable binary logistic regression analyses were executed with odds ratio at 95% confidence intervals at p  < .05. Results A total of 72(17.4%) participants reported at least one side effect following vaccination. The proportion prevalence was higher after the first dose than that of the second dose and the difference was also found to be statistically significant. In the multivariable logistic regression analysis female participants (AOR = 3.39, 95% CI =  1.53, 7.52), participants with a history of regular medication use (AOR = 3.34, 95% CI  =  1.52, 7.33), participants aged 55 and above (AOR = 2.93, 95% CI  =  1.23, 7.01), and participants who had taken only the first dose (AOR = 14.81, 95% CI  =  6.40, 34.31) were more likely to develop side effects for COVID 19 vaccination compared to their counterparts. Conclusion A significant number (17.4%) of participants reported at least one side effect following vaccination. Sex, medication, occupation, age, and type of vaccination dose were factors statistically associated with the reported side effects.
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spelling doaj.art-bdbd52717c99486cac35d02b8c276fad2023-04-28T06:33:22ZengSAGE PublishingSAGE Open Nursing2377-96082023-04-01910.1177/23779608231172358Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, EthiopiaEbrahim Abdela Siraj MSc0Ashagrachew Tewabe Yayehrad MSc1Zewdu Yilma MSc2Tamyalew Getahun MSc3Mequannent Sharew Melaku MSc4Gizachew Kassahun Bizuneh MSc5Zemene Demelash Kifle MSc6Dawit Kumilachew Yimenu MSc7 Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia Department of Pharmacy, College of Medicine and Health Sciences, Bahir Dar University, Bahir Dar, Ethiopia Addis Alem Primary Hospital, Amhara Regional Health Beuro, Bahir Dar, Ethiopia Department of Health Informatics, Institute of Public Health, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Department of Pharmacognosy, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Department of Pharmacology, School of Pharmacy, College of Medicine and Health Sciences, University of Gondar, Gondar, Ethiopia Discipline of Pharmacy, School of Allied Health, The University of Western AustraliaIntroduction The lack of local side effect profiles for vaccines could hinder vaccination uptake. Since all COVID-19 vaccines are brand-new medications, it is crucial to keep track of any safety related concern. Objective This study is aimed to investigate post-vaccination side effects of COVID-19 vaccines and associated factors in Bahir Dar city. Method An institutional-based cross-sectional study was conducted among vaccinated clients. A simple random and a systematic random sampling method were used to select the health facilities and the participants, respectively. Bi-variable and multivariable binary logistic regression analyses were executed with odds ratio at 95% confidence intervals at p  < .05. Results A total of 72(17.4%) participants reported at least one side effect following vaccination. The proportion prevalence was higher after the first dose than that of the second dose and the difference was also found to be statistically significant. In the multivariable logistic regression analysis female participants (AOR = 3.39, 95% CI =  1.53, 7.52), participants with a history of regular medication use (AOR = 3.34, 95% CI  =  1.52, 7.33), participants aged 55 and above (AOR = 2.93, 95% CI  =  1.23, 7.01), and participants who had taken only the first dose (AOR = 14.81, 95% CI  =  6.40, 34.31) were more likely to develop side effects for COVID 19 vaccination compared to their counterparts. Conclusion A significant number (17.4%) of participants reported at least one side effect following vaccination. Sex, medication, occupation, age, and type of vaccination dose were factors statistically associated with the reported side effects.https://doi.org/10.1177/23779608231172358
spellingShingle Ebrahim Abdela Siraj MSc
Ashagrachew Tewabe Yayehrad MSc
Zewdu Yilma MSc
Tamyalew Getahun MSc
Mequannent Sharew Melaku MSc
Gizachew Kassahun Bizuneh MSc
Zemene Demelash Kifle MSc
Dawit Kumilachew Yimenu MSc
Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia
SAGE Open Nursing
title Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia
title_full Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia
title_fullStr Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia
title_full_unstemmed Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia
title_short Post COVID-19 Vaccination Side Effects and Associated Factors Among Vaccinated Clients in Bahir Dar City, Ethiopia
title_sort post covid 19 vaccination side effects and associated factors among vaccinated clients in bahir dar city ethiopia
url https://doi.org/10.1177/23779608231172358
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