Target Identification and Validation of (+)-2-(1-Hydroxyl-4-Oxocyclohexyl) Ethyl Caffeate, an Anti-Inflammatory Natural Product

Target Identification and Validation of (+)-2-(1-Hydroxyl-4-Oxocyclohexyl) Ethyl Caffeate, an Anti-Inflammatory Natural Product

(+)-2-(1-hydroxyl-4-oxocyclohexyl) ethyl caffeate (HOEC) was isolated from Incarvillea mairei var. granditlora (Wehrhahn) Grierson. The plants of the Incarvillea genus have long been used as folk medicines for the treatment of inflammation-related diseases in China. 5-Lipoxygenase (5-LOX), a key enz...

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Bibliographic Details
Main Authors: L. Li, H-W. Zeng, F. Liu, J-G. Zhang, R-C. Yue, W-Q. Lu, X. Yuan, W-X. Dai, H. Yuan, Q-Y. Sun, J. Huang, H-L. Li, Y-S. Li, L. Shan, W-D. Zhang
Format: Article
Language:English
Published: SAGE Publishing 2012-09-01
Series:European Journal of Inflammation
Online Access:https://doi.org/10.1177/1721727X1201000306

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