Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification

Protective role of small extracellular vesicles derived from HUVECs treated with AGEs in diabetic vascular calcification

Abstract The pathogenesis of vascular calcification in diabetic patients remains elusive. As an effective information transmitter, small extracellular vesicles (sEVs) carry abundant microRNAs (miRNAs) that regulate the physiological and pathological states of recipient cells. In the present study, s...

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Bibliographic Details
Main Authors: Bei Guo, Su-Kang Shan, Feng Xu, Xiao Lin, Fu-Xing-zi Li, Yi Wang, Qiu-Shuang Xu, Ming-Hui Zheng, Li-Min Lei, Chang-Chun Li, Zhi-Ang Zhou, Muhammad Hasnain Ehsan Ullah, Feng Wu, Xiao-Bo Liao, Ling-Qing Yuan
Format: Article
Language:English
Published: BMC 2022-07-01
Series:Journal of Nanobiotechnology
Subjects:
Vascular calcification
Diabetes
sEVs
miR-126-5p
Endothelial cells
Online Access:https://doi.org/10.1186/s12951-022-01529-z

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