Diacerein improves left ventricular remodeling and cardiac function by reducing the inflammatory response after myocardial infarction.

Diacerein improves left ventricular remodeling and cardiac function by reducing the inflammatory response after myocardial infarction.

The inflammatory response has been implicated in the pathogenesis of left ventricular (LV) remodeling after myocardial infarction (MI). An anthraquinone compound with anti-inflammatory properties, diacerein inhibits the synthesis and activity of pro-inflammatory cytokines, such as tumor necrosis fac...

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Main Authors: Anali Galluce Torina, Karla Reichert, Fany Lima, Karlos Alexandre de Souza Vilarinho, Pedro Paulo Martins de Oliveira, Helison Rafael Pereira do Carmo, Daniela Diógenes de Carvalho, Mário José Abdalla Saad, Andrei Carvalho Sposito, Orlando Petrucci
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376692?pdf=render

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