Determination of genes and microRNAs involved in the resistance to fludarabine <it>in vivo </it>in chronic lymphocytic leukemia

Determination of genes and microRNAs involved in the resistance to fludarabine <it>in vivo </it>in chronic lymphocytic leukemia

<p>Abstract</p> <p>Background</p> <p>Chronic lymphocytic leukemia (CLL) cells are often affected by genomic aberrations targeting key regulatory genes. Although fludarabine is the standard first line therapy to treat CLL, only few data are available about the resistance...

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Main Authors: Muller Arnaud, Bernardin François, Leners Bernadette, Van Moer Kris, Aouali Nasséra, El Khoury Victoria, Wenner Thomas, Poirel Hélène A, Vallar Laurent, Palissot Valérie, Moussay Etienne, Cornillet-Lefebvre Pascale, Delmer Alain, Duhem Caroline, Ries Fernand, van Dyck Eric, Berchem Guy
Format: Article
Language:English
Published: BMC 2010-05-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/115

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