Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway

Protective Effect of GIP against Monosodium Glutamate-Induced Ferroptosis in Mouse Hippocampal HT-22 Cells through the MAPK Signaling Pathway

The effect of glucose-dependent insulinotropic polypeptide (GIP) on cells under oxidative stress induced by glutamate, a neurotransmitter, and the underlying molecular mechanisms were assessed in the present study. We found that in the pre-treatment of HT-22 cells with glutamate in a dose-dependent...

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Bibliographic Details
Main Authors:	Jiwon Ko, Soyoung Jang, Wookbong Kwon, Si-Yong Kim, Soyeon Jang, Eungyung Kim, Young-Rae Ji, Sijun Park, Myoung-Ok Kim, Seong-Kyoon Choi, Dong-Hyung Cho, Hyun-Shik Lee, Su-Geun Lim, Zae-Young Ryoo
Format:	Article
Language:	English
Published:	MDPI AG 2022-01-01
Series:	Antioxidants
Subjects:	monosodium glutamate neurotoxicity ferroptosis oxidative stress cellular oxidative homeostasis mouse hippocampal HT-22 cells
Online Access:	https://www.mdpi.com/2076-3921/11/2/189

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