The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery
Context Musculoskeletal injuries may be painful, troublesome, life limiting and also one of the global health problems. There has been considerable amount of interest during the past two decades to stem cells and tissue engineering techniques in orthopedic surgery, especially to manage spe...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Kashan University of Medical Sciences
2016-08-01
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| Series: | Archives of Trauma Research |
| Online Access: |
http://archtrauma.com/?page=article&article_id=37976
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| _version_ | 1797728855563173888 |
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| author | Akpancar Tatar Turgut Akyildiz Ekinci |
| author_facet | Akpancar Tatar Turgut Akyildiz Ekinci |
| author_sort | Akpancar |
| collection | DOAJ |
| description | Context
Musculoskeletal injuries may be painful, troublesome, life limiting and also one of the global health problems. There has been considerable amount of interest during the past two decades to stem cells and tissue engineering techniques in orthopedic surgery, especially to manage special and compulsive injuries within the musculoskeletal system.
Evidence Acquisition
The aim of this study was to present a literature review regarding the most recent progress in stem cell procedures and current indications in orthopedics clinical care practice. The Medline and PubMed library databases were searched for the articles related with stem cell procedures in the field of orthopedic surgery and additionally the reference list of each article was also included to provide a comprehensive evaluation.
Results
Various sources of stem cells have been studied for orthopedics clinical care practice. Stem cell therapy has successfully used for major orthopedic procedures in terms of bone-joint injuries (fractures-bone defects, nonunion, and spinal injuries), osteoarthritis-cartilage defects, ligament-tendon injuries, femoral head osteonecrosis and osteogenesis imperfecta. Stem cells have also used in bone tissue engineering in combining with the scaffolds and provided faster and better healing of tissues.
Conclusions
Large amounts of preclinical studies have been made of stem cells and there is an increasing interest to perform these studies within the human population but preclinical studies are insufficient; therefore, much more and efficient studies should be conducted to evaluate the efficacy and safety of stem cells. |
| first_indexed | 2024-03-12T11:20:03Z |
| format | Article |
| id | doaj.art-bdde29e3f8504bcba7ac97c92b9c08e4 |
| institution | Directory Open Access Journal |
| issn | 2251-953X 2251-9599 |
| language | English |
| last_indexed | 2024-03-12T11:20:03Z |
| publishDate | 2016-08-01 |
| publisher | Kashan University of Medical Sciences |
| record_format | Article |
| series | Archives of Trauma Research |
| spelling | doaj.art-bdde29e3f8504bcba7ac97c92b9c08e42023-09-02T01:08:01ZengKashan University of Medical SciencesArchives of Trauma Research2251-953X2251-95992016-08-015410.5812/atr.37976The Current Perspectives of Stem Cell Therapy in Orthopedic SurgeryAkpancarTatarTurgutAkyildizEkinciContext Musculoskeletal injuries may be painful, troublesome, life limiting and also one of the global health problems. There has been considerable amount of interest during the past two decades to stem cells and tissue engineering techniques in orthopedic surgery, especially to manage special and compulsive injuries within the musculoskeletal system. Evidence Acquisition The aim of this study was to present a literature review regarding the most recent progress in stem cell procedures and current indications in orthopedics clinical care practice. The Medline and PubMed library databases were searched for the articles related with stem cell procedures in the field of orthopedic surgery and additionally the reference list of each article was also included to provide a comprehensive evaluation. Results Various sources of stem cells have been studied for orthopedics clinical care practice. Stem cell therapy has successfully used for major orthopedic procedures in terms of bone-joint injuries (fractures-bone defects, nonunion, and spinal injuries), osteoarthritis-cartilage defects, ligament-tendon injuries, femoral head osteonecrosis and osteogenesis imperfecta. Stem cells have also used in bone tissue engineering in combining with the scaffolds and provided faster and better healing of tissues. Conclusions Large amounts of preclinical studies have been made of stem cells and there is an increasing interest to perform these studies within the human population but preclinical studies are insufficient; therefore, much more and efficient studies should be conducted to evaluate the efficacy and safety of stem cells. http://archtrauma.com/?page=article&article_id=37976 |
| spellingShingle | Akpancar Tatar Turgut Akyildiz Ekinci The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery Archives of Trauma Research |
| title | The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery |
| title_full | The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery |
| title_fullStr | The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery |
| title_full_unstemmed | The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery |
| title_short | The Current Perspectives of Stem Cell Therapy in Orthopedic Surgery |
| title_sort | current perspectives of stem cell therapy in orthopedic surgery |
| url |
http://archtrauma.com/?page=article&article_id=37976
|
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