Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level
Objectives: We set forth to estimate the number of those with Parkinson's disease (PD) in Hungary, a country with a single-payer health insurance system covering 10 million inhabitants.Methods: We analyzed all hospital and outpatient reports from neurological services and pharmacy reports of pr...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-06-01
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| Series: | Frontiers in Neurology |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fneur.2019.00640/full |
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| author | Szabolcs Szatmári Szabolcs Szatmári Szabolcs Szatmári András Ajtay András Ajtay Mónika Bálint Annamária Takáts Ferenc Oberfrank Dániel Bereczki Dániel Bereczki |
| author_facet | Szabolcs Szatmári Szabolcs Szatmári Szabolcs Szatmári András Ajtay András Ajtay Mónika Bálint Annamária Takáts Ferenc Oberfrank Dániel Bereczki Dániel Bereczki |
| author_sort | Szabolcs Szatmári |
| collection | DOAJ |
| description | Objectives: We set forth to estimate the number of those with Parkinson's disease (PD) in Hungary, a country with a single-payer health insurance system covering 10 million inhabitants.Methods: We analyzed all hospital and outpatient reports from neurological services and pharmacy reports of prescription refills. We cross-checked clinically administered diagnosis of PD with prescription refills of antiparkinsonian medications using record linkage. We used the ICD-10 code of G20 in any diagnostic category to find all cases with possible PD. For case certification those patients were considered to have PD who were recorded with G20 code in at least 2 calendar years. For a more conservative estimation we determined the number of those who also refilled antiparkinsonian medication.Results: Between 2010 and 2012 there were 46,383 subjects with certified PD by clinical criteria. Crude and age-standardized incidence were 49/100,000/year (95% CI: 45–53), and 56/100,000/year (95% CI: 51–60). Crude and age standardized prevalence rates were 404/100,000 (95% CI: 392–416) and 471/100,000 (95% CI: 456–485). Of all clinically certified PD patients 72% refilled antiparkinsonian medications.Discussion: The incidence and prevalence of PD in Hungary is higher than earlier estimates, which should be considered in organizing healthcare services for this patient group. |
| first_indexed | 2024-12-11T09:13:56Z |
| format | Article |
| id | doaj.art-bdde7b31568643efaf84b266fea9e836 |
| institution | Directory Open Access Journal |
| issn | 1664-2295 |
| language | English |
| last_indexed | 2024-12-11T09:13:56Z |
| publishDate | 2019-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neurology |
| spelling | doaj.art-bdde7b31568643efaf84b266fea9e8362022-12-22T01:13:26ZengFrontiers Media S.A.Frontiers in Neurology1664-22952019-06-011010.3389/fneur.2019.00640451107Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide LevelSzabolcs Szatmári0Szabolcs Szatmári1Szabolcs Szatmári2András Ajtay3András Ajtay4Mónika Bálint5Annamária Takáts6Ferenc Oberfrank7Dániel Bereczki8Dániel Bereczki9János Szentágothai Doctoral School of Neurosciences, Semmelweis University, Budapest, HungaryDepartment of Neurology, Semmelweis University, Budapest, HungaryMTA-SE Neuroepidemiological Research Group, Budapest, HungaryDepartment of Neurology, Semmelweis University, Budapest, HungaryMTA-SE Neuroepidemiological Research Group, Budapest, HungaryHungarian Academy of Sciences Centre for Economic and Regional Studies, Budapest, HungaryDepartment of Neurology, Semmelweis University, Budapest, HungaryInstitute of Experimental Medicine of the Hungarian Academy of Sciences, Budapest, HungaryDepartment of Neurology, Semmelweis University, Budapest, HungaryMTA-SE Neuroepidemiological Research Group, Budapest, HungaryObjectives: We set forth to estimate the number of those with Parkinson's disease (PD) in Hungary, a country with a single-payer health insurance system covering 10 million inhabitants.Methods: We analyzed all hospital and outpatient reports from neurological services and pharmacy reports of prescription refills. We cross-checked clinically administered diagnosis of PD with prescription refills of antiparkinsonian medications using record linkage. We used the ICD-10 code of G20 in any diagnostic category to find all cases with possible PD. For case certification those patients were considered to have PD who were recorded with G20 code in at least 2 calendar years. For a more conservative estimation we determined the number of those who also refilled antiparkinsonian medication.Results: Between 2010 and 2012 there were 46,383 subjects with certified PD by clinical criteria. Crude and age-standardized incidence were 49/100,000/year (95% CI: 45–53), and 56/100,000/year (95% CI: 51–60). Crude and age standardized prevalence rates were 404/100,000 (95% CI: 392–416) and 471/100,000 (95% CI: 456–485). Of all clinically certified PD patients 72% refilled antiparkinsonian medications.Discussion: The incidence and prevalence of PD in Hungary is higher than earlier estimates, which should be considered in organizing healthcare services for this patient group.https://www.frontiersin.org/article/10.3389/fneur.2019.00640/fullParkinson's diseaseincidenceprevalencerecord linkageHungary |
| spellingShingle | Szabolcs Szatmári Szabolcs Szatmári Szabolcs Szatmári András Ajtay András Ajtay Mónika Bálint Annamária Takáts Ferenc Oberfrank Dániel Bereczki Dániel Bereczki Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level Frontiers in Neurology Parkinson's disease incidence prevalence record linkage Hungary |
| title | Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level |
| title_full | Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level |
| title_fullStr | Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level |
| title_full_unstemmed | Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level |
| title_short | Linking Individual Patient Data to Estimate Incidence and Prevalence of Parkinson's Disease by Comparing Reports of Neurological Services and Pharmacy Prescription Refills at a Nationwide Level |
| title_sort | linking individual patient data to estimate incidence and prevalence of parkinson s disease by comparing reports of neurological services and pharmacy prescription refills at a nationwide level |
| topic | Parkinson's disease incidence prevalence record linkage Hungary |
| url | https://www.frontiersin.org/article/10.3389/fneur.2019.00640/full |
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