Aggressive surgery for advanced ovarian cancer performed by a multidisciplinary team: A retrospective analysis on a large series of patients

Background: To evaluate the impact of extended surgical treatment performed by a team of gynecologists and general surgeons on postoperative morbidity and survival of patients with advanced ovarian cancer. Methods: We collected data of 156 patients with advanced ovarian cancer stage IIb-III-IV accor...

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Main Authors: Stefano Rausei, Stefano Uccella, Valentina D'Alessandro, Baldo Gisone, Francesco Frattini, Georgios Lianos, Francesca Rovera, Luigi Boni, Gianlorenzo Dionigi, Fabio Ghezzi
Format: Article
Language:English
Published: Elsevier 2019-07-01
Series:Surgery Open Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2589845019300120
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Summary:Background: To evaluate the impact of extended surgical treatment performed by a team of gynecologists and general surgeons on postoperative morbidity and survival of patients with advanced ovarian cancer. Methods: We collected data of 156 patients with advanced ovarian cancer stage IIb-III-IV according to International Federation of Gynecology and Obstetrics classification and treated with primary cytoreduction. End points were perioperative and postoperative complications and cancer-related survival. Results: In 51 cases (51/156, 32.7%) a multivisceral resection was completed. Postoperative complications occurred in 52 cases (33.3%). The duration of the surgical procedure as well as the need for diaphragmatic peritonectomy were the factors independently associated with the development of postoperative complications. Five-year cancer-related survival rate was of 50.7%: only histotype and residual tumor resulted significantly associated. Conclusions: Our results highlight the importance of a team of gynecologists and general surgeons with specific interests and skills to achieve cytoreduction as rapidly as possible, even when it implies very complex maneuvers.
ISSN:2589-8450