Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography
Gilbert's syndrome (GS) is an autosomal inherited disorder characterized by relative deficiency of glucuronyl transferase and poor uptake of unconjugated bilirubin by hepatocytes. Cardiac surgery on cardiopulmonary bypass (CPB) in these patients triggers further hepatic dysfunction. Transesopha...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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| Series: | Saudi Journal of Anaesthesia |
| Subjects: | |
| Online Access: | http://www.saudija.org/article.asp?issn=1658-354X;year=2017;volume=11;issue=1;spage=89;epage=92;aulast=Nagaraja |
| _version_ | 1811227567832694784 |
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| author | P S Nagaraja Naveen G Singh S Subash N Manjunatha C G Prabhushankar N Sathish |
| author_facet | P S Nagaraja Naveen G Singh S Subash N Manjunatha C G Prabhushankar N Sathish |
| author_sort | P S Nagaraja |
| collection | DOAJ |
| description | Gilbert's syndrome (GS) is an autosomal inherited disorder characterized by relative deficiency of glucuronyl transferase and poor uptake of unconjugated bilirubin by hepatocytes. Cardiac surgery on cardiopulmonary bypass (CPB) in these patients triggers further hepatic dysfunction. Transesophageal echocardiography (TEE) and Doppler assessment of hepatic vein help in assessing hepatic blood flow (HBF) during cardiac surgery. Here, we discuss anesthetic management and role of TEE in maintaining HBF perioperatively in a 25-year-old male patient with GS undergoing double valve replacement with tricuspid valve plasty. TEE-guided HBF monitoring and management of hepatic perfusion by modifying anesthetic and CPB protocol resulted in the favorable outcome. |
| first_indexed | 2024-04-12T09:44:39Z |
| format | Article |
| id | doaj.art-bde55f66172f48d69687e7eb2976f81b |
| institution | Directory Open Access Journal |
| issn | 1658-354X |
| language | English |
| last_indexed | 2024-04-12T09:44:39Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Saudi Journal of Anaesthesia |
| spelling | doaj.art-bde55f66172f48d69687e7eb2976f81b2022-12-22T03:37:59ZengWolters Kluwer Medknow PublicationsSaudi Journal of Anaesthesia1658-354X2017-01-01111899210.4103/1658-354X.197335Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiographyP S NagarajaNaveen G SinghS SubashN ManjunathaC G PrabhushankarN SathishGilbert's syndrome (GS) is an autosomal inherited disorder characterized by relative deficiency of glucuronyl transferase and poor uptake of unconjugated bilirubin by hepatocytes. Cardiac surgery on cardiopulmonary bypass (CPB) in these patients triggers further hepatic dysfunction. Transesophageal echocardiography (TEE) and Doppler assessment of hepatic vein help in assessing hepatic blood flow (HBF) during cardiac surgery. Here, we discuss anesthetic management and role of TEE in maintaining HBF perioperatively in a 25-year-old male patient with GS undergoing double valve replacement with tricuspid valve plasty. TEE-guided HBF monitoring and management of hepatic perfusion by modifying anesthetic and CPB protocol resulted in the favorable outcome.http://www.saudija.org/article.asp?issn=1658-354X;year=2017;volume=11;issue=1;spage=89;epage=92;aulast=NagarajaBilirubingeneral anesthesiaGilbert syndrometransesophageal echocardiography |
| spellingShingle | P S Nagaraja Naveen G Singh S Subash N Manjunatha C G Prabhushankar N Sathish Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography Saudi Journal of Anaesthesia Bilirubin general anesthesia Gilbert syndrome transesophageal echocardiography |
| title | Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography |
| title_full | Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography |
| title_fullStr | Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography |
| title_full_unstemmed | Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography |
| title_short | Anesthetic management of a case of Gilbert's syndrome for mitral and aortic valve replacement: Role of transesophageal echocardiography |
| title_sort | anesthetic management of a case of gilbert s syndrome for mitral and aortic valve replacement role of transesophageal echocardiography |
| topic | Bilirubin general anesthesia Gilbert syndrome transesophageal echocardiography |
| url | http://www.saudija.org/article.asp?issn=1658-354X;year=2017;volume=11;issue=1;spage=89;epage=92;aulast=Nagaraja |
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