Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report

Regenerative endodontic procedures are biologically based procedures which deal with the regeneration of pulp-like tissue, more idealistically the pulp-dentin complex. The regeneration of this pulp-dentin complex in an infected necrotic tooth with an open apex is possible only when the canal is effe...

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Main Authors: Raji Viola Solomon, Umrana Faizuddin, Sushma Shravani Guniganti, Shefali Waghray
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2015-01-01
Series:Indian Journal of Dental Research
Subjects:
Online Access:http://www.ijdr.in/article.asp?issn=0970-9290;year=2015;volume=26;issue=1;spage=90;epage=95;aulast=Solomon
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author Raji Viola Solomon
Umrana Faizuddin
Sushma Shravani Guniganti
Shefali Waghray
author_facet Raji Viola Solomon
Umrana Faizuddin
Sushma Shravani Guniganti
Shefali Waghray
author_sort Raji Viola Solomon
collection DOAJ
description Regenerative endodontic procedures are biologically based procedures which deal with the regeneration of pulp-like tissue, more idealistically the pulp-dentin complex. The regeneration of this pulp-dentin complex in an infected necrotic tooth with an open apex is possible only when the canal is effectively disinfected. Though there are various procedures for treating open apex ranging from Ca(OH) 2 apexification, mineral trioxide aggregate apexification and surgical approach, regeneration of tissues has always taken superior hand over the repair of tissues. The mechanics behind the regenerative endodontic procedures is that despite the tooth being necrotic, some pulp tissue can survive apically which under favorable conditions proliferate to aid in the process of regeneration. In the past 2 decades, an increased understanding of the physiological roles of platelets in wound healing and after tissue injury has led to the idea of using platelets as therapeutic tools in the field regenerative endodontics. In the present case report with an open apex, high sterilization protocol is followed using triple antibiotic paste as intra-canal medicament, followed which platelet rich fibrin is used as the regenerative material of choice. Over an 18-month follow-up period, clinically patient is asymptomatic and radiographically there is complete regression of the periapical lesion and initiation of the root end closure.
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spelling doaj.art-bde91a543b564daca2662eb8563770fb2022-12-22T01:57:47ZengWolters Kluwer Medknow PublicationsIndian Journal of Dental Research0970-92901998-36032015-01-01261909510.4103/0970-9290.156823Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case reportRaji Viola SolomonUmrana FaizuddinSushma Shravani GunigantiShefali WaghrayRegenerative endodontic procedures are biologically based procedures which deal with the regeneration of pulp-like tissue, more idealistically the pulp-dentin complex. The regeneration of this pulp-dentin complex in an infected necrotic tooth with an open apex is possible only when the canal is effectively disinfected. Though there are various procedures for treating open apex ranging from Ca(OH) 2 apexification, mineral trioxide aggregate apexification and surgical approach, regeneration of tissues has always taken superior hand over the repair of tissues. The mechanics behind the regenerative endodontic procedures is that despite the tooth being necrotic, some pulp tissue can survive apically which under favorable conditions proliferate to aid in the process of regeneration. In the past 2 decades, an increased understanding of the physiological roles of platelets in wound healing and after tissue injury has led to the idea of using platelets as therapeutic tools in the field regenerative endodontics. In the present case report with an open apex, high sterilization protocol is followed using triple antibiotic paste as intra-canal medicament, followed which platelet rich fibrin is used as the regenerative material of choice. Over an 18-month follow-up period, clinically patient is asymptomatic and radiographically there is complete regression of the periapical lesion and initiation of the root end closure.http://www.ijdr.in/article.asp?issn=0970-9290;year=2015;volume=26;issue=1;spage=90;epage=95;aulast=SolomonDental traumamaturogenesisopen apexplatelet rich fibrinregenerationtriple antibiotic paste
spellingShingle Raji Viola Solomon
Umrana Faizuddin
Sushma Shravani Guniganti
Shefali Waghray
Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report
Indian Journal of Dental Research
Dental trauma
maturogenesis
open apex
platelet rich fibrin
regeneration
triple antibiotic paste
title Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report
title_full Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report
title_fullStr Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report
title_full_unstemmed Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report
title_short Analysis of the rate of maturogenesis of a traumatized Cvek′s stage 3 anterior tooth treated with platelet-rich fibrin as a regenerative tool using three-dimensional cone-beam computed tomography: An original case report
title_sort analysis of the rate of maturogenesis of a traumatized cvek s stage 3 anterior tooth treated with platelet rich fibrin as a regenerative tool using three dimensional cone beam computed tomography an original case report
topic Dental trauma
maturogenesis
open apex
platelet rich fibrin
regeneration
triple antibiotic paste
url http://www.ijdr.in/article.asp?issn=0970-9290;year=2015;volume=26;issue=1;spage=90;epage=95;aulast=Solomon
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