Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature
Contrast-induced encephalopathy (CIE) is an uncommon complication associated with contrast exposure during angiographic procedures that is usually transient but occasionally leads to permanent complications or death. Due to the low incidence of CIE, there are still insufficient reports. This study w...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Cellular Neuroscience |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fncel.2022.1070357/full |
| _version_ | 1797961942751510528 |
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| author | Yujing Zhang Yujing Zhang Jiancheng Zhang Jiancheng Zhang Shiying Yuan Shiying Yuan Huaqing Shu Huaqing Shu |
| author_facet | Yujing Zhang Yujing Zhang Jiancheng Zhang Jiancheng Zhang Shiying Yuan Shiying Yuan Huaqing Shu Huaqing Shu |
| author_sort | Yujing Zhang |
| collection | DOAJ |
| description | Contrast-induced encephalopathy (CIE) is an uncommon complication associated with contrast exposure during angiographic procedures that is usually transient but occasionally leads to permanent complications or death. Due to the low incidence of CIE, there are still insufficient reports. This study was used to summarize the clinical features of CIE through a case report and systematic review. We summarized and reviewed 127 patients with CIE, and we found that the total incidence of CIE between men and women had no difference (49.61 and 50.39%, respectively), but the average age in female patients with CIE was older than that in male patients (62.19 and 58.77 years, respectively). Interestingly, the incidence of female patients with CIE in the poor prognosis group was significantly higher than that in the good prognosis group (62.50 and 36.51%, respectively), and the average age of these female patients in the poor prognosis group was younger than that in the good prognosis group (61.39 and 62.82 years, respectively). The contrast medium types were mainly nonionic (79.69 and 73.02%, respectively) and low-osmolar (54.69 and 71.43%, respectively) in both groups. Importantly, the total contrast media administrated in patients with poor prognoses was greater than that administrated in patients with good prognoses (198.07 and 188.60 ml, respectively). In addition, comorbidities in both groups included hypertension (55.91%), diabetes mellitus (20.47%), previous contrast history (15.75%), renal impairment (11.81%), and hyperlipidemia (3.15%). The percentage of patients with cerebral angiography was significantly higher in the poor prognosis group than that in the good prognosis group (37.50 and 9.52%, respectively), whereas the percentage of patients with coronary angiography in both groups had the opposite results (35.94 and 77.78%, respectively). In conclusion, CIE may not always have a benign outcome and can cause permanent deficits. Female gender, younger age, the higher dose of contrast medium, and the procedure of cerebral angiography may be related to the patient’s poor prognosis. |
| first_indexed | 2024-04-11T01:06:49Z |
| format | Article |
| id | doaj.art-bdedba6f3d5344c19a3ac3830f2e34d2 |
| institution | Directory Open Access Journal |
| issn | 1662-5102 |
| language | English |
| last_indexed | 2024-04-11T01:06:49Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
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| series | Frontiers in Cellular Neuroscience |
| spelling | doaj.art-bdedba6f3d5344c19a3ac3830f2e34d22023-01-04T12:24:35ZengFrontiers Media S.A.Frontiers in Cellular Neuroscience1662-51022023-01-011610.3389/fncel.2022.10703571070357Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literatureYujing Zhang0Yujing Zhang1Jiancheng Zhang2Jiancheng Zhang3Shiying Yuan4Shiying Yuan5Huaqing Shu6Huaqing Shu7Department of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaInstitute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaInstitute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaInstitute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaDepartment of Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaInstitute of Anesthesia and Critical Care Medicine, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ChinaContrast-induced encephalopathy (CIE) is an uncommon complication associated with contrast exposure during angiographic procedures that is usually transient but occasionally leads to permanent complications or death. Due to the low incidence of CIE, there are still insufficient reports. This study was used to summarize the clinical features of CIE through a case report and systematic review. We summarized and reviewed 127 patients with CIE, and we found that the total incidence of CIE between men and women had no difference (49.61 and 50.39%, respectively), but the average age in female patients with CIE was older than that in male patients (62.19 and 58.77 years, respectively). Interestingly, the incidence of female patients with CIE in the poor prognosis group was significantly higher than that in the good prognosis group (62.50 and 36.51%, respectively), and the average age of these female patients in the poor prognosis group was younger than that in the good prognosis group (61.39 and 62.82 years, respectively). The contrast medium types were mainly nonionic (79.69 and 73.02%, respectively) and low-osmolar (54.69 and 71.43%, respectively) in both groups. Importantly, the total contrast media administrated in patients with poor prognoses was greater than that administrated in patients with good prognoses (198.07 and 188.60 ml, respectively). In addition, comorbidities in both groups included hypertension (55.91%), diabetes mellitus (20.47%), previous contrast history (15.75%), renal impairment (11.81%), and hyperlipidemia (3.15%). The percentage of patients with cerebral angiography was significantly higher in the poor prognosis group than that in the good prognosis group (37.50 and 9.52%, respectively), whereas the percentage of patients with coronary angiography in both groups had the opposite results (35.94 and 77.78%, respectively). In conclusion, CIE may not always have a benign outcome and can cause permanent deficits. Female gender, younger age, the higher dose of contrast medium, and the procedure of cerebral angiography may be related to the patient’s poor prognosis.https://www.frontiersin.org/articles/10.3389/fncel.2022.1070357/fullcerebral angiographycontrast-induced encephalopathyneurological deficitprognosisrisk factor |
| spellingShingle | Yujing Zhang Yujing Zhang Jiancheng Zhang Jiancheng Zhang Shiying Yuan Shiying Yuan Huaqing Shu Huaqing Shu Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature Frontiers in Cellular Neuroscience cerebral angiography contrast-induced encephalopathy neurological deficit prognosis risk factor |
| title | Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature |
| title_full | Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature |
| title_fullStr | Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature |
| title_full_unstemmed | Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature |
| title_short | Contrast-induced encephalopathy and permanent neurological deficit following cerebral angiography: A case report and review of the literature |
| title_sort | contrast induced encephalopathy and permanent neurological deficit following cerebral angiography a case report and review of the literature |
| topic | cerebral angiography contrast-induced encephalopathy neurological deficit prognosis risk factor |
| url | https://www.frontiersin.org/articles/10.3389/fncel.2022.1070357/full |
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