Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study
Abstract Background: Infertility is a global health issue and is reported differently worldwide. Objective: To assess the longitudinal trends of primary and secondary infertility prevalence rate (PSIPR) per 100,000 across all countries during past decades. Materials and Methods: The PSIPR was extrac...
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| Format: | Article |
| Language: | English |
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Shahid Sadoughi University of Medical Sciences
2022-01-01
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| Series: | International Journal of Reproductive BioMedicine |
| Subjects: | |
| Online Access: | https://doi.org/10.18502/ijrm.v20i1.10407 |
| _version_ | 1819122131369197568 |
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| author | Nasrin Borumandnia Hamid Alavi Majd Naghmeh Khadembashi Hojat Alaii |
| author_facet | Nasrin Borumandnia Hamid Alavi Majd Naghmeh Khadembashi Hojat Alaii |
| author_sort | Nasrin Borumandnia |
| collection | DOAJ |
| description | Abstract Background: Infertility is a global health issue and is reported differently worldwide. Objective: To assess the longitudinal trends of primary and secondary infertility prevalence rate (PSIPR) per 100,000 across all countries during past decades. Materials and Methods: The PSIPR was extracted from the Global Burden of Disease database for 195 countries during 1993-2017. The longitudinal trends of PSIPR were explored across the seven epidemiological regions designated by the Global Burden of Disease. Results: Globally, the PSIPR was lower among men than women. Over time, the prevalence of primary infertility in men and women had a decreasing trend of -9.3 and -11.6 in high-income countries. Other regions have seen an increase, the highest being in South Asian women, and men of the Middle East and North Africa, with rates of change of 40.9 and 19.0, respectively. Over time, the secondary infertility prevalence in women of Central Asia, Central Europe and Eastern Europe, as well as of high-income countries, has been declining (rates of change of -16.9 and -11.7, respectively). Other regions have been on the rise, with the highest increase among women of the Middle East, North Africa, and South Asia (trend of 119.9 and 83.4, respectively), and in South Asian men (trend of 48.4). Conclusion: The overall trend of infertility prevalence shows a downward trajectory in high-income and developed countries and an upward trend in others. These findings might be explained by missed cases of infertility due to a low tendency for reproduction and the presence of more infertility treatment facilities in these regions. |
| first_indexed | 2024-12-22T06:47:35Z |
| format | Article |
| id | doaj.art-bdf1cded31f64be9a822b57614703249 |
| institution | Directory Open Access Journal |
| issn | 2476-4108 2476-3772 |
| language | English |
| last_indexed | 2024-12-22T06:47:35Z |
| publishDate | 2022-01-01 |
| publisher | Shahid Sadoughi University of Medical Sciences |
| record_format | Article |
| series | International Journal of Reproductive BioMedicine |
| spelling | doaj.art-bdf1cded31f64be9a822b576147032492022-12-21T18:35:15ZengShahid Sadoughi University of Medical SciencesInternational Journal of Reproductive BioMedicine2476-41082476-37722022-01-01201374610.18502/ijrm.v20i1.10407ijrm.v20i1.10407Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional studyNasrin Borumandnia0Hamid Alavi Majd1Naghmeh Khadembashi2Hojat Alaii3 Urology and Nephrology Research Centre, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Foreign Languages Education, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran. Department of Biostatistics, School of Allied Medical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Abstract Background: Infertility is a global health issue and is reported differently worldwide. Objective: To assess the longitudinal trends of primary and secondary infertility prevalence rate (PSIPR) per 100,000 across all countries during past decades. Materials and Methods: The PSIPR was extracted from the Global Burden of Disease database for 195 countries during 1993-2017. The longitudinal trends of PSIPR were explored across the seven epidemiological regions designated by the Global Burden of Disease. Results: Globally, the PSIPR was lower among men than women. Over time, the prevalence of primary infertility in men and women had a decreasing trend of -9.3 and -11.6 in high-income countries. Other regions have seen an increase, the highest being in South Asian women, and men of the Middle East and North Africa, with rates of change of 40.9 and 19.0, respectively. Over time, the secondary infertility prevalence in women of Central Asia, Central Europe and Eastern Europe, as well as of high-income countries, has been declining (rates of change of -16.9 and -11.7, respectively). Other regions have been on the rise, with the highest increase among women of the Middle East, North Africa, and South Asia (trend of 119.9 and 83.4, respectively), and in South Asian men (trend of 48.4). Conclusion: The overall trend of infertility prevalence shows a downward trajectory in high-income and developed countries and an upward trend in others. These findings might be explained by missed cases of infertility due to a low tendency for reproduction and the presence of more infertility treatment facilities in these regions.https://doi.org/10.18502/ijrm.v20i1.10407infertility, global burden of disease, longitudinal studies. |
| spellingShingle | Nasrin Borumandnia Hamid Alavi Majd Naghmeh Khadembashi Hojat Alaii Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study International Journal of Reproductive BioMedicine infertility, global burden of disease, longitudinal studies. |
| title | Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study |
| title_full | Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study |
| title_fullStr | Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study |
| title_full_unstemmed | Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study |
| title_short | Worldwide trend analysis of primary and secondary infertility rates over past decades: A cross-sectional study |
| title_sort | worldwide trend analysis of primary and secondary infertility rates over past decades a cross sectional study |
| topic | infertility, global burden of disease, longitudinal studies. |
| url | https://doi.org/10.18502/ijrm.v20i1.10407 |
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