Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds
Fluor-hydroxyapatite (FHA) is a biomaterial with dental and orthopedic potential that is highly regarded as a result of bioactivity and high biocompatibility. Chitosan is used as a growth promoting agent in the tissues of the tooth and bone. Composite scaffold from these biomaterials is used as a pa...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Hindawi-Wiley
2023-01-01
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Series: | Advances in Polymer Technology |
Online Access: | http://dx.doi.org/10.1155/2023/2758621 |
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author | Majid Salehi Sahar Molzemi |
author_facet | Majid Salehi Sahar Molzemi |
author_sort | Majid Salehi |
collection | DOAJ |
description | Fluor-hydroxyapatite (FHA) is a biomaterial with dental and orthopedic potential that is highly regarded as a result of bioactivity and high biocompatibility. Chitosan is used as a growth promoting agent in the tissues of the tooth and bone. Composite scaffold from these biomaterials is used as a pattern of natural bone and tooth grafts in tissue engineering. In this study FHA was synthesized through coprecipitation method. Then chitosan/FHA composites with different amounts of FHA (15 and 30 wt%) were prepared via freeze drying way. Structural and physical characteristics of the scaffolds were determined by powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) spectra, and morphological properties of the scaffolds were investigated using SEM evaluation. The compressive strength, water-uptake capacity, and biodegradation behavior of scaffolds were performed, as well. The results indicated that chitosan/30%FHA scaffold showed more compressive strength, lower biodegradation in phosphate buffer solution after 4 weeks. Therefore, it might be a suitable scaffold for tooth engineering. |
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id | doaj.art-bdf2a6c6abb8475c8e2dd9640277257b |
institution | Directory Open Access Journal |
issn | 1098-2329 |
language | English |
last_indexed | 2024-03-13T00:17:41Z |
publishDate | 2023-01-01 |
publisher | Hindawi-Wiley |
record_format | Article |
series | Advances in Polymer Technology |
spelling | doaj.art-bdf2a6c6abb8475c8e2dd9640277257b2023-07-12T00:00:00ZengHindawi-WileyAdvances in Polymer Technology1098-23292023-01-01202310.1155/2023/2758621Fabrication and Mechanical Properties of Chitosan/FHA ScaffoldsMajid Salehi0Sahar Molzemi1Department of Tissue EngineeringStudent Research CommitteeFluor-hydroxyapatite (FHA) is a biomaterial with dental and orthopedic potential that is highly regarded as a result of bioactivity and high biocompatibility. Chitosan is used as a growth promoting agent in the tissues of the tooth and bone. Composite scaffold from these biomaterials is used as a pattern of natural bone and tooth grafts in tissue engineering. In this study FHA was synthesized through coprecipitation method. Then chitosan/FHA composites with different amounts of FHA (15 and 30 wt%) were prepared via freeze drying way. Structural and physical characteristics of the scaffolds were determined by powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) spectra, and morphological properties of the scaffolds were investigated using SEM evaluation. The compressive strength, water-uptake capacity, and biodegradation behavior of scaffolds were performed, as well. The results indicated that chitosan/30%FHA scaffold showed more compressive strength, lower biodegradation in phosphate buffer solution after 4 weeks. Therefore, it might be a suitable scaffold for tooth engineering.http://dx.doi.org/10.1155/2023/2758621 |
spellingShingle | Majid Salehi Sahar Molzemi Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds Advances in Polymer Technology |
title | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
title_full | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
title_fullStr | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
title_full_unstemmed | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
title_short | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
title_sort | fabrication and mechanical properties of chitosan fha scaffolds |
url | http://dx.doi.org/10.1155/2023/2758621 |
work_keys_str_mv | AT majidsalehi fabricationandmechanicalpropertiesofchitosanfhascaffolds AT saharmolzemi fabricationandmechanicalpropertiesofchitosanfhascaffolds |