Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds
Fluor-hydroxyapatite (FHA) is a biomaterial with dental and orthopedic potential that is highly regarded as a result of bioactivity and high biocompatibility. Chitosan is used as a growth promoting agent in the tissues of the tooth and bone. Composite scaffold from these biomaterials is used as a pa...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi-Wiley
2023-01-01
|
| Series: | Advances in Polymer Technology |
| Online Access: | http://dx.doi.org/10.1155/2023/2758621 |
| _version_ | 1797782844040282112 |
|---|---|
| author | Majid Salehi Sahar Molzemi |
| author_facet | Majid Salehi Sahar Molzemi |
| author_sort | Majid Salehi |
| collection | DOAJ |
| description | Fluor-hydroxyapatite (FHA) is a biomaterial with dental and orthopedic potential that is highly regarded as a result of bioactivity and high biocompatibility. Chitosan is used as a growth promoting agent in the tissues of the tooth and bone. Composite scaffold from these biomaterials is used as a pattern of natural bone and tooth grafts in tissue engineering. In this study FHA was synthesized through coprecipitation method. Then chitosan/FHA composites with different amounts of FHA (15 and 30 wt%) were prepared via freeze drying way. Structural and physical characteristics of the scaffolds were determined by powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) spectra, and morphological properties of the scaffolds were investigated using SEM evaluation. The compressive strength, water-uptake capacity, and biodegradation behavior of scaffolds were performed, as well. The results indicated that chitosan/30%FHA scaffold showed more compressive strength, lower biodegradation in phosphate buffer solution after 4 weeks. Therefore, it might be a suitable scaffold for tooth engineering. |
| first_indexed | 2024-03-13T00:17:41Z |
| format | Article |
| id | doaj.art-bdf2a6c6abb8475c8e2dd9640277257b |
| institution | Directory Open Access Journal |
| issn | 1098-2329 |
| language | English |
| last_indexed | 2024-03-13T00:17:41Z |
| publishDate | 2023-01-01 |
| publisher | Hindawi-Wiley |
| record_format | Article |
| series | Advances in Polymer Technology |
| spelling | doaj.art-bdf2a6c6abb8475c8e2dd9640277257b2023-07-12T00:00:00ZengHindawi-WileyAdvances in Polymer Technology1098-23292023-01-01202310.1155/2023/2758621Fabrication and Mechanical Properties of Chitosan/FHA ScaffoldsMajid Salehi0Sahar Molzemi1Department of Tissue EngineeringStudent Research CommitteeFluor-hydroxyapatite (FHA) is a biomaterial with dental and orthopedic potential that is highly regarded as a result of bioactivity and high biocompatibility. Chitosan is used as a growth promoting agent in the tissues of the tooth and bone. Composite scaffold from these biomaterials is used as a pattern of natural bone and tooth grafts in tissue engineering. In this study FHA was synthesized through coprecipitation method. Then chitosan/FHA composites with different amounts of FHA (15 and 30 wt%) were prepared via freeze drying way. Structural and physical characteristics of the scaffolds were determined by powder X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR) spectra, and morphological properties of the scaffolds were investigated using SEM evaluation. The compressive strength, water-uptake capacity, and biodegradation behavior of scaffolds were performed, as well. The results indicated that chitosan/30%FHA scaffold showed more compressive strength, lower biodegradation in phosphate buffer solution after 4 weeks. Therefore, it might be a suitable scaffold for tooth engineering.http://dx.doi.org/10.1155/2023/2758621 |
| spellingShingle | Majid Salehi Sahar Molzemi Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds Advances in Polymer Technology |
| title | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
| title_full | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
| title_fullStr | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
| title_full_unstemmed | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
| title_short | Fabrication and Mechanical Properties of Chitosan/FHA Scaffolds |
| title_sort | fabrication and mechanical properties of chitosan fha scaffolds |
| url | http://dx.doi.org/10.1155/2023/2758621 |
| work_keys_str_mv | AT majidsalehi fabricationandmechanicalpropertiesofchitosanfhascaffolds AT saharmolzemi fabricationandmechanicalpropertiesofchitosanfhascaffolds |