Quantification of glucose and glycerol diffusion in myocardium

The results on determination of glucose and glycerol diffusion coefficients in myocardium tissue are presented. The method is based on the measurement and analysis of temporal dependence of tissue optical collimated transmittance under action of a hyperosmotic agent. This temporal tissue response is...

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Bibliographic Details
Main Authors: Daria K. Tuchina, Alexey N. Bashkatov, Elina A. Genina, Valery V. Tuchin
Format: Article
Language:English
Published: World Scientific Publishing 2015-05-01
Series:Journal of Innovative Optical Health Sciences
Subjects:
Online Access:http://www.worldscientific.com/doi/pdf/10.1142/S1793545815410060
Description
Summary:The results on determination of glucose and glycerol diffusion coefficients in myocardium tissue are presented. The method is based on the measurement and analysis of temporal dependence of tissue optical collimated transmittance under action of a hyperosmotic agent. This temporal tissue response is related to the rate of the agent and water diffusion in a tissue. The diffusion coefficients for tissue fluid fluxes at glucose and glycerol application to the myocardium at 20°C have been estimated as (4.75 ± 3.40) × 10-7 and (7.71 ± 4.63) × 10-7 cm2/s, respectively.
ISSN:1793-5458
1793-7205