Genetic variants in miRNA processing genes and pre-miRNAs are associated with the risk of chronic lymphocytic leukemia.

Genetic variants in miRNA processing genes and pre-miRNAs are associated with the risk of chronic lymphocytic leukemia.

Genome wide association studies (GWAS) have identified several low-penetrance susceptibility alleles in chronic lymphocytic leukemia (CLL). Nevertheless, these studies scarcely study regions that are implicated in non-coding molecules such as microRNAs (miRNAs). Abnormalities in miRNAs, as altered e...

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Bibliographic Details
Main Authors: Idoia Martin-Guerrero, Angela Gutierrez-Camino, Elixabet Lopez-Lopez, Nerea Bilbao-Aldaiturriaga, Maria Pombar-Gomez, Maite Ardanaz, Africa Garcia-Orad
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4368096?pdf=render

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