Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report
Abstract Background Haemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by various types of viruses of the genus Hantavirus, which are mainly transmitted by contact with the infected rodents and their droppings. Pregnancy complicated with HFRS is rare; however, adverse...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-12-01
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| Series: | BMC Infectious Diseases |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12879-020-05638-8 |
| _version_ | 1828932560685629440 |
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| author | Xiang Ying Xiaoli Lai Xiaoxiao Jin Linghong Cai Xiaotian Li |
| author_facet | Xiang Ying Xiaoli Lai Xiaoxiao Jin Linghong Cai Xiaotian Li |
| author_sort | Xiang Ying |
| collection | DOAJ |
| description | Abstract Background Haemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by various types of viruses of the genus Hantavirus, which are mainly transmitted by contact with the infected rodents and their droppings. Pregnancy complicated with HFRS is rare; however, adverse maternal and foetal outcomes may be noted. In this report, we describe a case involving a pregnant woman with HFRS who was in a state of multiple organ dysfunction syndrome (MODS) and was successfully treated with continuous renal replacement therapy (CRRT). Case presentation A 32-year-old pregnant woman at 29 weeks of gestation was hospitalised for a fever and upper respiratory tract infection due to HFRS in winter. Persistent fever, coagulation disorder, thrombocytopenia, electrolyte imbalance, abnormal liver function, and renal failure were noted during the progression of the disease. The patient was treated with CRRT. She recovered after 21 days, and delivered a live infant by caesarean section at 38 weeks of gestation. Furthermore, obvious abnormalities were not detected during the follow-up of the mother and infant at 42 days, 3 months, 6 months, and 1 year after the delivery. Conclusions Early diagnosis, timely application of CRRT, and comprehensive treatment may be essential for the successful treatment of patients with HFRS during pregnancy. |
| first_indexed | 2024-12-14T01:04:07Z |
| format | Article |
| id | doaj.art-be0367b990de40428c30592d429daea7 |
| institution | Directory Open Access Journal |
| issn | 1471-2334 |
| language | English |
| last_indexed | 2024-12-14T01:04:07Z |
| publishDate | 2020-12-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Infectious Diseases |
| spelling | doaj.art-be0367b990de40428c30592d429daea72022-12-21T23:23:05ZengBMCBMC Infectious Diseases1471-23342020-12-012011510.1186/s12879-020-05638-8Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case reportXiang Ying0Xiaoli Lai1Xiaoxiao Jin2Linghong Cai3Xiaotian Li4Department of Obstetrics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical UniversityDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical UniversityDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical UniversityDepartment of Obstetrics, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical UniversityDepartment of Obstetrics, Obstetrics and Gynecology Hospital of Fudan UniversityAbstract Background Haemorrhagic fever with renal syndrome (HFRS) is a natural epidemic disease caused by various types of viruses of the genus Hantavirus, which are mainly transmitted by contact with the infected rodents and their droppings. Pregnancy complicated with HFRS is rare; however, adverse maternal and foetal outcomes may be noted. In this report, we describe a case involving a pregnant woman with HFRS who was in a state of multiple organ dysfunction syndrome (MODS) and was successfully treated with continuous renal replacement therapy (CRRT). Case presentation A 32-year-old pregnant woman at 29 weeks of gestation was hospitalised for a fever and upper respiratory tract infection due to HFRS in winter. Persistent fever, coagulation disorder, thrombocytopenia, electrolyte imbalance, abnormal liver function, and renal failure were noted during the progression of the disease. The patient was treated with CRRT. She recovered after 21 days, and delivered a live infant by caesarean section at 38 weeks of gestation. Furthermore, obvious abnormalities were not detected during the follow-up of the mother and infant at 42 days, 3 months, 6 months, and 1 year after the delivery. Conclusions Early diagnosis, timely application of CRRT, and comprehensive treatment may be essential for the successful treatment of patients with HFRS during pregnancy.https://doi.org/10.1186/s12879-020-05638-8Haemorrhagic fever with renal syndromePregnancyContinuous renal replacement therapyCase report |
| spellingShingle | Xiang Ying Xiaoli Lai Xiaoxiao Jin Linghong Cai Xiaotian Li Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report BMC Infectious Diseases Haemorrhagic fever with renal syndrome Pregnancy Continuous renal replacement therapy Case report |
| title | Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report |
| title_full | Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report |
| title_fullStr | Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report |
| title_full_unstemmed | Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report |
| title_short | Continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy: a case report |
| title_sort | continuous renal replacement therapy rescues severe haemorrhagic fever with renal syndrome in pregnancy a case report |
| topic | Haemorrhagic fever with renal syndrome Pregnancy Continuous renal replacement therapy Case report |
| url | https://doi.org/10.1186/s12879-020-05638-8 |
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