Oxidation of blood lipoproteins in patients with cerebrovascular diseases
An comparative analysis of oxidation of low density lipoproteins/verylow density lipoproteins, and a clinical severity of acute and chronic cerebrovascular diseases was performed. To assess the intensity of lipid peroxidation we estimated several kinetic parameters of ferrous iron-induced chemilumin...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Research Center of Neurology
2017-02-01
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| Series: | Анналы клинической и экспериментальной неврологии |
| Subjects: | |
| Online Access: | https://annaly-nevrologii.com/journal/pathID/article/viewFile/194/34 |
| _version_ | 1811337911395680256 |
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| author | T. N. Fedorova M. Yu. Maksimova Yu. Ya. Varakin G. V. Gornostaeva A. A. Logvinenko E. V. Gnedovskaya Z. A. Suslina |
| author_facet | T. N. Fedorova M. Yu. Maksimova Yu. Ya. Varakin G. V. Gornostaeva A. A. Logvinenko E. V. Gnedovskaya Z. A. Suslina |
| author_sort | T. N. Fedorova |
| collection | DOAJ |
| description | An comparative analysis of oxidation of low density lipoproteins/verylow density lipoproteins, and a clinical severity of acute and chronic cerebrovascular diseases was performed. To assess the intensity of lipid peroxidation we estimated several kinetic parameters of ferrous iron-induced chemiluminescence.
In this article we present the results of the clinical and biochemical assessment of 412 patients with wide spectrum of cerebrovascular diseases, such as acute stroke (n=179), chronic cerebrovascular disease (n=105), hypertensive crisis (n=60), hypertension without cerebral symptoms (n=47), and initial stages of chronic cerebrovascular insufficiency (n=21). We showed that lipid oxidation becomes evident even on the early stages of cerebrovascular diseases, and then progresses gradually following clinical severity of the disease, and the intensity of the peroxidation rises significantly in chronic and acute forms of cerebrovascular diseases. |
| first_indexed | 2024-04-13T18:02:55Z |
| format | Article |
| id | doaj.art-be05d41ff3c44acc81f0476a44f7abd8 |
| institution | Directory Open Access Journal |
| issn | 2075-5473 2409-2533 |
| language | English |
| last_indexed | 2024-04-13T18:02:55Z |
| publishDate | 2017-02-01 |
| publisher | Research Center of Neurology |
| record_format | Article |
| series | Анналы клинической и экспериментальной неврологии |
| spelling | doaj.art-be05d41ff3c44acc81f0476a44f7abd82022-12-22T02:36:11ZengResearch Center of NeurologyАнналы клинической и экспериментальной неврологии2075-54732409-25332017-02-0181303310.17816/psaic19496Oxidation of blood lipoproteins in patients with cerebrovascular diseasesT. N. Fedorova0M. Yu. Maksimova1Yu. Ya. Varakin2G. V. Gornostaeva3A. A. Logvinenko4E. V. Gnedovskaya5Z. A. Suslina6Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)Research Center of Neurology, Russian Academy of Medical Sciences (Moscow)An comparative analysis of oxidation of low density lipoproteins/verylow density lipoproteins, and a clinical severity of acute and chronic cerebrovascular diseases was performed. To assess the intensity of lipid peroxidation we estimated several kinetic parameters of ferrous iron-induced chemiluminescence. In this article we present the results of the clinical and biochemical assessment of 412 patients with wide spectrum of cerebrovascular diseases, such as acute stroke (n=179), chronic cerebrovascular disease (n=105), hypertensive crisis (n=60), hypertension without cerebral symptoms (n=47), and initial stages of chronic cerebrovascular insufficiency (n=21). We showed that lipid oxidation becomes evident even on the early stages of cerebrovascular diseases, and then progresses gradually following clinical severity of the disease, and the intensity of the peroxidation rises significantly in chronic and acute forms of cerebrovascular diseases.https://annaly-nevrologii.com/journal/pathID/article/viewFile/194/34lipid peroxidationchemiluminescencecerebrovascular diseases |
| spellingShingle | T. N. Fedorova M. Yu. Maksimova Yu. Ya. Varakin G. V. Gornostaeva A. A. Logvinenko E. V. Gnedovskaya Z. A. Suslina Oxidation of blood lipoproteins in patients with cerebrovascular diseases Анналы клинической и экспериментальной неврологии lipid peroxidation chemiluminescence cerebrovascular diseases |
| title | Oxidation of blood lipoproteins in patients with cerebrovascular diseases |
| title_full | Oxidation of blood lipoproteins in patients with cerebrovascular diseases |
| title_fullStr | Oxidation of blood lipoproteins in patients with cerebrovascular diseases |
| title_full_unstemmed | Oxidation of blood lipoproteins in patients with cerebrovascular diseases |
| title_short | Oxidation of blood lipoproteins in patients with cerebrovascular diseases |
| title_sort | oxidation of blood lipoproteins in patients with cerebrovascular diseases |
| topic | lipid peroxidation chemiluminescence cerebrovascular diseases |
| url | https://annaly-nevrologii.com/journal/pathID/article/viewFile/194/34 |
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