Neurofilament Light Chains in Systemic Amyloidosis: A Systematic Review

Neurofilament Light Chains in Systemic Amyloidosis: A Systematic Review

Peripheral and autonomic neuropathy are common disease manifestations in systemic amyloidosis. The neurofilament light chain (NfL), a neuron-specific biomarker, is released into the blood and cerebrospinal fluid after neuronal damage. There is a need for an early and sensitive blood biomarker for po...

Full description

Bibliographic Details
Main Authors:	Milou Berends, Hans L. A. Nienhuis, David Adams, Chafic Karam, Marco Luigetti, Michael Polydefkis, Mary M. Reilly, Yoshiki Sekijima, Bouke P. C. Hazenberg
Format:	Article
Language:	English
Published:	MDPI AG 2024-03-01
Series:	International Journal of Molecular Sciences
Subjects:	systemic amyloidosis hereditary transthyretin amyloid immunoglobulin light chain amyloid transthyretin gene-variant carrier biomarker neurofilament light chain
Online Access:	https://www.mdpi.com/1422-0067/25/7/3770

Similar Items

Molecular Mechanisms of Cardiac Amyloidosis
by: Yukihiro Saito, et al.
Published: (2021-12-01)

From Clinical Clues to Final Diagnosis: The Return of Detective Work to Clinical Medicine in Cardiac Amyloidosis
by: Hani Sabbour, et al.
Published: (2021-06-01)

British Society of Echocardiography guideline for the transthoracic echocardiographic assessment of cardiac amyloidosis
by: William E. Moody, et al.
Published: (2023-08-01)

Amiloidosi, Ovvero Quando le Proteine Fibrillano. Storia, Fisiopatologia e Classificazione di Una Malattia Non Poi così Rara
by: Franco Bergesio
Published: (2017-05-01)

Multimodal Imaging and Biomarkers in Cardiac Amyloidosis
by: Mi-Hyang Jung, et al.
Published: (2022-03-01)

Diagnostic Challenges and Solutions in Systemic Amyloidosis
by: Rivka Goldis, et al.
Published: (2023-02-01)

Musculoskeletal pathology as an early warning sign of systemic amyloidosis: a systematic review of amyloid deposition and orthopedic surgery
by: Austin E. Wininger, et al.
Published: (2021-01-01)

Current Evidence Supporting the Role of Immune Response in ATTRv Amyloidosis
by: Domenico Plantone, et al.
Published: (2023-09-01)

Specific Therapy for Transthyretin Cardiac Amyloidosis: A Systematic Literature Review and Evidence‐Based Recommendations
by: Nuno Marques, et al.
Published: (2020-10-01)

State of the Art of Cardiac Amyloidosis
by: Nabil Belfeki, et al.
Published: (2023-03-01)

Abdominal Fat Biopsy for the Diagnosis of Cardiac Amyloidosis
by: Alberto Aimo, MD, et al.
Published: (2020-07-01)

Ocular Involvement in Hereditary Amyloidosis
by: Angelo Maria Minnella, et al.
Published: (2021-06-01)

Strong positive light chain immunostaining in a patient with transthyretin amyloidosis
by: Jiao Chen, et al.
Published: (2023-12-01)

Coexistence of Light Chain and Transthyretin Cardiac Amyloidosis
by: Abhishek Gami, MD, et al.
Published: (2024-04-01)

Updated Evaluation of the Safety, Efficacy and Tolerability of Tafamidis in the Treatment of Hereditary Transthyretin Amyloid Polyneuropathy
by: Falcão de Campos C, et al.
Published: (2023-02-01)

Utility and pitfalls of the electrocardiogram in the evaluation of cardiac amyloidosis
by: Perryn Lin Fei Ng, et al.
Published: (2022-07-01)

Transthyretin amyloid cardiomyopathy: Treatment pipeline, clinical trials, and challenges
by: Sweety Sharma, et al.
Published: (2021-01-01)

Editorial: Proceedings and predictions in cardiac amyloidosis: unsolved mysteries and challenges for the future
by: Aldostefano Porcari, et al.
Published: (2023-07-01)

Leptomeningeal amyloidosis: features of the clinical picture (clinical observation)
by: E. I. Safiulina, et al.
Published: (2022-12-01)

Clinical features and predictors of atrial fibrillation in patients with light‐chain or transthyretin cardiac amyloidosis
by: Maria Papathanasiou, et al.
Published: (2022-06-01)

High-Sensitivity Cardiac Troponin T to Exclude Cardiac Involvement in TTR Variant Carriers and ATTRv Amyloidosis Patients
by: Hendrea S. A. Tingen, et al.
Published: (2024-01-01)

Impact of tricuspid regurgitation on survival in patients with cardiac amyloidosis
by: Jerome Fagot, et al.
Published: (2021-02-01)

Transthyretin Misfolding, A Fatal Structural Pathogenesis Mechanism
by: Jin-Beom Si, et al.
Published: (2021-04-01)

Gross hematuria: An unusual presenting symptom of systemic wild-type transthyretin amyloidosis
by: Sage A. Vincent, et al.
Published: (2021-11-01)

Case Report: Systemic Amyloidosis Involving the Heart and Skeletal Muscle
by: Pinchao Lv, et al.
Published: (2022-04-01)

Transthyretin cardiac amyloidosis: an under-diagnosed cause of heart failure
by: Gabriela Molina O, et al.
Published: (2014-11-01)

New simple and quick method to analyze serum variant transthyretins: direct MALDI method for the screening of hereditary transthyretin amyloidosis
by: Toshiya Nomura, et al.
Published: (2019-05-01)

Diagnostic performance of imaging investigations in detecting and differentiating cardiac amyloidosis: a systematic review and meta‐analysis
by: Jack Brownrigg, et al.
Published: (2019-10-01)

Vitreous Amyloidosis as the Presenting Symptom of Familial Amyloid Polyneuropathy TTR Val30Met in a Portuguese Patient
by: Mariana Seca, et al.
Published: (2014-03-01)

Progress and challenges in the treatment of cardiac amyloidosis: a review of the literature
by: Robert Daniel Adam, et al.
Published: (2021-08-01)

Late-Onset Hereditary Transthyretin Amyloidosis Val30Met in an Elderly Person in a Non-Endemic Area
by: Wang S, et al.
Published: (2022-06-01)

Modulation of the Mechanisms Driving Transthyretin Amyloidosis
by: Filipa Bezerra, et al.
Published: (2020-12-01)

The impact of inotersen on Neuropathy Impairment Score in patients with hereditary transthyretin amyloidosis with polyneuropathy
by: Aaron Yarlas, et al.
Published: (2023-03-01)

The short and long‐term characteristics and outcomes of patients with grade 1 myocardial uptake on cardiac scintigraphy
by: Osnat Itzhaki Ben Zadok, et al.
Published: (2023-06-01)

Advances in the treatment of hereditary transthyretin amyloidosis: A review
by: Morie A. Gertz, et al.
Published: (2019-09-01)

A clinical case of hereditary transthyretin amyloidosis. Case report
by: Anastasia A. Shoshina, et al.
Published: (2023-05-01)

Healthcare resource use associated with the diagnosis of transthyretin amyloidosis cardiomyopathy
by: Clint Asher, et al.
Published: (2022-01-01)

Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis
by: Faruk Uğur Doğan, et al.
Published: (2019-03-01)

AL amyloidosis with non-amyloid forming monoclonal immunoglobulin deposition; a case mimicking AHL amyloidosis
by: Shun Manabe, et al.
Published: (2018-11-01)

Amyloid Burden Correlates with Electrocardiographic Findings in Patients with Cardiac Amyloidosis—Insights from Histology and Cardiac Magnetic Resonance Imaging
by: Franz Duca, et al.
Published: (2024-01-01)