Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study
Introduction: Previous literature related to postoperative outcomes after laparoscopic vs. open ileal pouch-anal anastomosis (IPAA) is primarily based on small numbers of patients from single institutions. The aim of this study is to evaluate these outcomes in a large number of patients using propen...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Elsevier
2022-09-01
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| Series: | Surgery in Practice and Science |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666262022000560 |
| _version_ | 1798004530516852736 |
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| author | Koby Herman Samantha Nemeth Bo Shen James M. Church Ravi P. Kiran |
| author_facet | Koby Herman Samantha Nemeth Bo Shen James M. Church Ravi P. Kiran |
| author_sort | Koby Herman |
| collection | DOAJ |
| description | Introduction: Previous literature related to postoperative outcomes after laparoscopic vs. open ileal pouch-anal anastomosis (IPAA) is primarily based on small numbers of patients from single institutions. The aim of this study is to evaluate these outcomes in a large number of patients using propensity score matching (PSM). Material and Methods: The ACS-NSQIP Program data files (2016-2019) were reviewed to identify patients who underwent an IPAA creation. The impact of surgical approach on operative and postoperative outcomes were evaluated. 1:1 propensity score matching (PSM) on all patient characteristics was used to obtain matched groups. Fisher's Exact/Chi-Squared tests were used to compare outcomes between groups. A Bonferroni correction was applied to the outcomes, with a p-value of 0.0031 representing statistical significance. Results: 1802 patients were identified, with 1001 patients in the laparoscopic group and 801 patients in the open group. PSM yielded 702 patients in each matched group. Median operative time was longer for laparoscopic IPAA (278vs218.5 minutes, p<0.001). Laparoscopic IPAA patients were less likely to develop superficial and deep SSIs (3.0% vs 6.6% p=0.003). There were no differences in in-hospital mortality (0.4% vs 0.0%, p=0.3), anastomotic leak (4.0% vs 3.3%, p=1.0), organ-space SSI (6.7% vs 6.0, p=1.0), or reoperation (5.7% vs 4.0%, p=0.2) between groups. Length of stay was lower after laparoscopic IPAA (5.0 vs 6.0 days, p=0.004). There were no differences between groups in other postoperative complications. Discussion: These data suggest that when matched for other confounding variables, laparoscopic IPAA is associated with reduced length of stay and superficial/deep SSIs when compared to open IPAA. Other surgical complications, including in-hospital mortality and anastomotic leak, are similar. Conclusion: Given the recovery benefit of the laparoscopic approach and the reduced SSI, laparoscopy should be the method of choice for the majority of patients undergoing IPAA. |
| first_indexed | 2024-04-11T12:26:06Z |
| format | Article |
| id | doaj.art-be06b10656554f5f867b43985736607f |
| institution | Directory Open Access Journal |
| issn | 2666-2620 |
| language | English |
| last_indexed | 2024-04-11T12:26:06Z |
| publishDate | 2022-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Surgery in Practice and Science |
| spelling | doaj.art-be06b10656554f5f867b43985736607f2022-12-22T04:23:57ZengElsevierSurgery in Practice and Science2666-26202022-09-0110100114Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP studyKoby Herman0Samantha Nemeth1Bo Shen2James M. Church3Ravi P. Kiran4Corresponding authors.; New York-Presbyterian/Columbia University Irving Medical Center, Colorectal Surgery, 161 Ft. Washington Ave. 8th Fl, New York, NY, 10032New York-Presbyterian/Columbia University Irving Medical Center, Colorectal Surgery, 161 Ft. Washington Ave. 8th Fl, New York, NY, 10032New York-Presbyterian/Columbia University Irving Medical Center, Colorectal Surgery, 161 Ft. Washington Ave. 8th Fl, New York, NY, 10032New York-Presbyterian/Columbia University Irving Medical Center, Colorectal Surgery, 161 Ft. Washington Ave. 8th Fl, New York, NY, 10032Corresponding authors.; New York-Presbyterian/Columbia University Irving Medical Center, Colorectal Surgery, 161 Ft. Washington Ave. 8th Fl, New York, NY, 10032Introduction: Previous literature related to postoperative outcomes after laparoscopic vs. open ileal pouch-anal anastomosis (IPAA) is primarily based on small numbers of patients from single institutions. The aim of this study is to evaluate these outcomes in a large number of patients using propensity score matching (PSM). Material and Methods: The ACS-NSQIP Program data files (2016-2019) were reviewed to identify patients who underwent an IPAA creation. The impact of surgical approach on operative and postoperative outcomes were evaluated. 1:1 propensity score matching (PSM) on all patient characteristics was used to obtain matched groups. Fisher's Exact/Chi-Squared tests were used to compare outcomes between groups. A Bonferroni correction was applied to the outcomes, with a p-value of 0.0031 representing statistical significance. Results: 1802 patients were identified, with 1001 patients in the laparoscopic group and 801 patients in the open group. PSM yielded 702 patients in each matched group. Median operative time was longer for laparoscopic IPAA (278vs218.5 minutes, p<0.001). Laparoscopic IPAA patients were less likely to develop superficial and deep SSIs (3.0% vs 6.6% p=0.003). There were no differences in in-hospital mortality (0.4% vs 0.0%, p=0.3), anastomotic leak (4.0% vs 3.3%, p=1.0), organ-space SSI (6.7% vs 6.0, p=1.0), or reoperation (5.7% vs 4.0%, p=0.2) between groups. Length of stay was lower after laparoscopic IPAA (5.0 vs 6.0 days, p=0.004). There were no differences between groups in other postoperative complications. Discussion: These data suggest that when matched for other confounding variables, laparoscopic IPAA is associated with reduced length of stay and superficial/deep SSIs when compared to open IPAA. Other surgical complications, including in-hospital mortality and anastomotic leak, are similar. Conclusion: Given the recovery benefit of the laparoscopic approach and the reduced SSI, laparoscopy should be the method of choice for the majority of patients undergoing IPAA.http://www.sciencedirect.com/science/article/pii/S2666262022000560Ileal pouch-anal anastomosisColorectalIBDLaparoscopic surgery |
| spellingShingle | Koby Herman Samantha Nemeth Bo Shen James M. Church Ravi P. Kiran Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study Surgery in Practice and Science Ileal pouch-anal anastomosis Colorectal IBD Laparoscopic surgery |
| title | Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study |
| title_full | Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study |
| title_fullStr | Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study |
| title_full_unstemmed | Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study |
| title_short | Laparoscopic ileal pouch-anal anastomosis reduces the risk of surgical site infections: An ACS-NSQIP study |
| title_sort | laparoscopic ileal pouch anal anastomosis reduces the risk of surgical site infections an acs nsqip study |
| topic | Ileal pouch-anal anastomosis Colorectal IBD Laparoscopic surgery |
| url | http://www.sciencedirect.com/science/article/pii/S2666262022000560 |
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