Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus
Summary: In the central nervous system, developmental and pathophysiologic conditions cause a large-scale reorganization of functional connectivity of neural circuits. Here, by using a mouse model for peripheral sensory nerve injury, we present a protocol for combined electrophysiological and anatom...
| Main Authors: | , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-09-01
|
| Series: | STAR Protocols |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666166721004500 |
| _version_ | 1819066709888204800 |
|---|---|
| author | Yoshifumi Ueta Mariko Miyata |
| author_facet | Yoshifumi Ueta Mariko Miyata |
| author_sort | Yoshifumi Ueta |
| collection | DOAJ |
| description | Summary: In the central nervous system, developmental and pathophysiologic conditions cause a large-scale reorganization of functional connectivity of neural circuits. Here, by using a mouse model for peripheral sensory nerve injury, we present a protocol for combined electrophysiological and anatomical techniques to identify neural basis of synaptic remodeling in the mouse whisker thalamus. Our protocol provides comprehensive approaches to analyze both structural and functional components of synaptic remodeling.For complete details on the use and execution of this protocol, please refer to Ueta and Miyata, (2021). |
| first_indexed | 2024-12-21T16:06:41Z |
| format | Article |
| id | doaj.art-be070aebcfea43b7ba73cc73956367af |
| institution | Directory Open Access Journal |
| issn | 2666-1667 |
| language | English |
| last_indexed | 2024-12-21T16:06:41Z |
| publishDate | 2021-09-01 |
| publisher | Elsevier |
| record_format | Article |
| series | STAR Protocols |
| spelling | doaj.art-be070aebcfea43b7ba73cc73956367af2022-12-21T18:57:53ZengElsevierSTAR Protocols2666-16672021-09-0123100743Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamusYoshifumi Ueta0Mariko Miyata1Division of Neurophysiology, Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo, 162-8666, Japan; Corresponding authorDivision of Neurophysiology, Department of Physiology, School of Medicine, Tokyo Women’s Medical University, Tokyo, 162-8666, Japan; Corresponding authorSummary: In the central nervous system, developmental and pathophysiologic conditions cause a large-scale reorganization of functional connectivity of neural circuits. Here, by using a mouse model for peripheral sensory nerve injury, we present a protocol for combined electrophysiological and anatomical techniques to identify neural basis of synaptic remodeling in the mouse whisker thalamus. Our protocol provides comprehensive approaches to analyze both structural and functional components of synaptic remodeling.For complete details on the use and execution of this protocol, please refer to Ueta and Miyata, (2021).http://www.sciencedirect.com/science/article/pii/S2666166721004500cell biologymicroscopymodel organismsneuroscience |
| spellingShingle | Yoshifumi Ueta Mariko Miyata Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus STAR Protocols cell biology microscopy model organisms neuroscience |
| title | Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus |
| title_full | Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus |
| title_fullStr | Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus |
| title_full_unstemmed | Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus |
| title_short | Electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus |
| title_sort | electrophysiological and anatomical characterization of synaptic remodeling in the mouse whisker thalamus |
| topic | cell biology microscopy model organisms neuroscience |
| url | http://www.sciencedirect.com/science/article/pii/S2666166721004500 |
| work_keys_str_mv | AT yoshifumiueta electrophysiologicalandanatomicalcharacterizationofsynapticremodelinginthemousewhiskerthalamus AT marikomiyata electrophysiologicalandanatomicalcharacterizationofsynapticremodelinginthemousewhiskerthalamus |