“Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence”
Background: Hand basal cell carcinoma is a rare and complex disorder. Due to the hand's anatomical features, managing hand BCC is challenging. Therefore, we have conducted this systematic review to investigate various clinical characteristics, investigations, and treatment options related to ha...
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| Format: | Article |
| Language: | English |
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Elsevier
2023-03-01
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| Series: | JPRAS Open |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352587822000870 |
| _version_ | 1797897250340339712 |
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| author | Hatan Mortada Rema Aldihan Nawaf Alhindi Rakan Abu alqam Muna Faisal Alnaim Abdullah E. Kattan |
| author_facet | Hatan Mortada Rema Aldihan Nawaf Alhindi Rakan Abu alqam Muna Faisal Alnaim Abdullah E. Kattan |
| author_sort | Hatan Mortada |
| collection | DOAJ |
| description | Background: Hand basal cell carcinoma is a rare and complex disorder. Due to the hand's anatomical features, managing hand BCC is challenging. Therefore, we have conducted this systematic review to investigate various clinical characteristics, investigations, and treatment options related to hand BCC. Furthermore, a meta-analysis was used to provide pooled recurrence rates. Methods: We conducted this review per the International Prospective Register of Systematic Reviews (PROSPERO) guidelines. This study performed a systematic literature review in February 2022 using the following electronic databases: Cochrane, MEDLINE, and EMBASE. Key terms include hand basal cell carcinoma, basal cell carcinoma, management, outcome, and recurrence. We evaluated articles according to predefined quality criteria. Results: The study included 9725 patients and 51 published articles. A total of 35 case reports, 2 case series, 1 prospective study, and the remaining retrospective studies were evaluated. An asymptomatic skin lesion was the main complaint. In 10 studies, Moh surgery was the most frequently used treatment method. In the seven studies included in the meta-analysis, the overall incidence rate of recurrence among the included patients was 1.49 cases per year. Conclusion: The optimal extent of surgical treatment is still controversial, though an early biopsy can help identify lesions at an early stage. It is the first study to provide occurrence rates based on a meta-analysis. Developing treatment guidelines for BCC of the hand will be the focus of future research. |
| first_indexed | 2024-04-10T07:55:40Z |
| format | Article |
| id | doaj.art-be087475898f45b48c0d930b680b3740 |
| institution | Directory Open Access Journal |
| issn | 2352-5878 |
| language | English |
| last_indexed | 2024-04-10T07:55:40Z |
| publishDate | 2023-03-01 |
| publisher | Elsevier |
| record_format | Article |
| series | JPRAS Open |
| spelling | doaj.art-be087475898f45b48c0d930b680b37402023-02-23T04:31:35ZengElsevierJPRAS Open2352-58782023-03-01354257“Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence”Hatan Mortada0Rema Aldihan1Nawaf Alhindi2Rakan Abu alqam3Muna Faisal Alnaim4Abdullah E. Kattan5Division of Plastic Surgery, Department of Surgery, King Saud University Medical City, King Saud University and Department of Plastic Surgery & Burn Unit, King Saud Medical City, Riyadh, Saudi ArabiaCollege of Medicine, King Saud University, Riyadh, Saudi Arabia; Corresponding author at: College of medicine, King Saud University, Riyadh, Saudi Arabia 12445, Riyadh, Saudi Arabia.College of Medicine, King Abdulaziz University, Rabigh, Saudi ArabiaCollege of Medicine, King Abdulaziz University, Jeddah, Saudi ArabiaCollege of Medicine, King Faisal University, AlAhsa, Saudi ArabiaDivision of Plastic Surgery, Department of Surgery, College of Medicine, King Saud University, Riyadh, Saudi ArabiaBackground: Hand basal cell carcinoma is a rare and complex disorder. Due to the hand's anatomical features, managing hand BCC is challenging. Therefore, we have conducted this systematic review to investigate various clinical characteristics, investigations, and treatment options related to hand BCC. Furthermore, a meta-analysis was used to provide pooled recurrence rates. Methods: We conducted this review per the International Prospective Register of Systematic Reviews (PROSPERO) guidelines. This study performed a systematic literature review in February 2022 using the following electronic databases: Cochrane, MEDLINE, and EMBASE. Key terms include hand basal cell carcinoma, basal cell carcinoma, management, outcome, and recurrence. We evaluated articles according to predefined quality criteria. Results: The study included 9725 patients and 51 published articles. A total of 35 case reports, 2 case series, 1 prospective study, and the remaining retrospective studies were evaluated. An asymptomatic skin lesion was the main complaint. In 10 studies, Moh surgery was the most frequently used treatment method. In the seven studies included in the meta-analysis, the overall incidence rate of recurrence among the included patients was 1.49 cases per year. Conclusion: The optimal extent of surgical treatment is still controversial, though an early biopsy can help identify lesions at an early stage. It is the first study to provide occurrence rates based on a meta-analysis. Developing treatment guidelines for BCC of the hand will be the focus of future research.http://www.sciencedirect.com/science/article/pii/S2352587822000870IIIRisk/prognostic study |
| spellingShingle | Hatan Mortada Rema Aldihan Nawaf Alhindi Rakan Abu alqam Muna Faisal Alnaim Abdullah E. Kattan “Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence” JPRAS Open III Risk/prognostic study |
| title | “Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence” |
| title_full | “Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence” |
| title_fullStr | “Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence” |
| title_full_unstemmed | “Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence” |
| title_short | “Basal cell carcinoma of the hand: A systematic review and meta-analysis of incidence of recurrence” |
| title_sort | basal cell carcinoma of the hand a systematic review and meta analysis of incidence of recurrence |
| topic | III Risk/prognostic study |
| url | http://www.sciencedirect.com/science/article/pii/S2352587822000870 |
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