Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion?
Abstract Background To find out if three-dimensional printing (3DP) off-the-shelf (OTS) prosthesis is superior to titanium mesh cages in anterior cervical corpectomy and fusion (ACCF) when treating single-segment degenerative cervical spondylotic myelopathy (DCSM). Methods DCSM patients underwent AC...
| Main Authors: | , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2024-01-01
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| Series: | BMC Musculoskeletal Disorders |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12891-024-07213-7 |
| _version_ | 1797341439159435264 |
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| author | Haoyu He Lei Fan Guohua Lü Xinyi Li Yunchao Li Ou Zhang Zejun Chen Hui Yuan Changyu Pan Xiaoxiao Wang Lei Kuang |
| author_facet | Haoyu He Lei Fan Guohua Lü Xinyi Li Yunchao Li Ou Zhang Zejun Chen Hui Yuan Changyu Pan Xiaoxiao Wang Lei Kuang |
| author_sort | Haoyu He |
| collection | DOAJ |
| description | Abstract Background To find out if three-dimensional printing (3DP) off-the-shelf (OTS) prosthesis is superior to titanium mesh cages in anterior cervical corpectomy and fusion (ACCF) when treating single-segment degenerative cervical spondylotic myelopathy (DCSM). Methods DCSM patients underwent ACCF from January 2016 to January 2019 in a single center were included. Patients were divided into the 3DP group (28) and the TMC group (23). The hospital stays, operation time, intraoperative blood loss, and the cost of hospitalization were compared. The Japanese Orthopedic Association (JOA) scores and Neck Disability Index (NDI) were recorded pre-operatively, 1 day, 3, 6, 12, and 24 months post-operatively. Radiological data was measured to evaluate fusion, subsidence, and cervical lordosis. Patients were sent with SF-36 to assess their health-related quality of life (HRQoL). Results The differences in operative time, intraoperative blood loss, and hospital stay were not statistically significant between groups (p > 0.05). Postoperative dysphagia occurred in 2 cases in the 3DP group and 3 cases in the TMC group, which all relieved one week later. The difference in improvement of JOA and NDI between the two groups was not statistically significant (p > 0.05). No hardware failure was found and bony fusion was achieved in all cases except one in the 3DP group. The difference in cervical lordosis (CL), fused segmental angle (FSA), mean vertebral height (MVH), and subsidence rates between groups at each follow-up time point was not statistically significant and the results of the SF-36 were similar (p > 0.05). The total cost was higher in the 3DP group with its higher graft cost (p < 0.05). Conclusion In treating single-segment DCSM with ACCF, both 3DP OTS prosthesis and TMC achieved satisfactory outcomes. However, the more costly 3DP OTS prosthesis was not able to reduce subsidence as it claimed. |
| first_indexed | 2024-03-08T10:18:03Z |
| format | Article |
| id | doaj.art-be08a3908a2048eb84283cba81c61c10 |
| institution | Directory Open Access Journal |
| issn | 1471-2474 |
| language | English |
| last_indexed | 2024-03-08T10:18:03Z |
| publishDate | 2024-01-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Musculoskeletal Disorders |
| spelling | doaj.art-be08a3908a2048eb84283cba81c61c102024-01-28T12:07:01ZengBMCBMC Musculoskeletal Disorders1471-24742024-01-0125111010.1186/s12891-024-07213-7Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion?Haoyu He0Lei Fan1Guohua Lü2Xinyi Li3Yunchao Li4Ou Zhang5Zejun Chen6Hui Yuan7Changyu Pan8Xiaoxiao Wang9Lei Kuang10Department of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, Third Hospital of ChangshaDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Medical Education, California University of Science and MedicineDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityDepartment of Spinal Surgery, The Second Xiangya Hospital of Central South UniversityAbstract Background To find out if three-dimensional printing (3DP) off-the-shelf (OTS) prosthesis is superior to titanium mesh cages in anterior cervical corpectomy and fusion (ACCF) when treating single-segment degenerative cervical spondylotic myelopathy (DCSM). Methods DCSM patients underwent ACCF from January 2016 to January 2019 in a single center were included. Patients were divided into the 3DP group (28) and the TMC group (23). The hospital stays, operation time, intraoperative blood loss, and the cost of hospitalization were compared. The Japanese Orthopedic Association (JOA) scores and Neck Disability Index (NDI) were recorded pre-operatively, 1 day, 3, 6, 12, and 24 months post-operatively. Radiological data was measured to evaluate fusion, subsidence, and cervical lordosis. Patients were sent with SF-36 to assess their health-related quality of life (HRQoL). Results The differences in operative time, intraoperative blood loss, and hospital stay were not statistically significant between groups (p > 0.05). Postoperative dysphagia occurred in 2 cases in the 3DP group and 3 cases in the TMC group, which all relieved one week later. The difference in improvement of JOA and NDI between the two groups was not statistically significant (p > 0.05). No hardware failure was found and bony fusion was achieved in all cases except one in the 3DP group. The difference in cervical lordosis (CL), fused segmental angle (FSA), mean vertebral height (MVH), and subsidence rates between groups at each follow-up time point was not statistically significant and the results of the SF-36 were similar (p > 0.05). The total cost was higher in the 3DP group with its higher graft cost (p < 0.05). Conclusion In treating single-segment DCSM with ACCF, both 3DP OTS prosthesis and TMC achieved satisfactory outcomes. However, the more costly 3DP OTS prosthesis was not able to reduce subsidence as it claimed.https://doi.org/10.1186/s12891-024-07213-7Cervical spondylotic myelopathyAnterior cervical corpectomy and fusion3D-printed prosthesisSubsidenceCost-effectiveness |
| spellingShingle | Haoyu He Lei Fan Guohua Lü Xinyi Li Yunchao Li Ou Zhang Zejun Chen Hui Yuan Changyu Pan Xiaoxiao Wang Lei Kuang Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion? BMC Musculoskeletal Disorders Cervical spondylotic myelopathy Anterior cervical corpectomy and fusion 3D-printed prosthesis Subsidence Cost-effectiveness |
| title | Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion? |
| title_full | Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion? |
| title_fullStr | Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion? |
| title_full_unstemmed | Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion? |
| title_short | Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion? |
| title_sort | myth or fact 3d printed off the shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion |
| topic | Cervical spondylotic myelopathy Anterior cervical corpectomy and fusion 3D-printed prosthesis Subsidence Cost-effectiveness |
| url | https://doi.org/10.1186/s12891-024-07213-7 |
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