Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah
Spinal anesthesia has some limitations that limits its use, such as limited duration of action in motoric and sensoric. This research aimed to provide an overview on the effect of adding clonidine 75 mcg to 12.5 mg 0.5% levobupivacaine on the motoric and sensoric blockade action duration in lower...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Indonesian |
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Universitas Padjadjaran
2015-04-01
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| Series: | Jurnal Anestesi Perioperatif |
| Online Access: | http://journal.fk.unpad.ac.id/index.php/jap/article/view/374 |
| _version_ | 1811191785174597632 |
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| author | Fadlyansyah Ramli Doddy Tavianto Tinni T. Maskoen |
| author_facet | Fadlyansyah Ramli Doddy Tavianto Tinni T. Maskoen |
| author_sort | Fadlyansyah Ramli |
| collection | DOAJ |
| description | Spinal anesthesia has some limitations that limits its use, such as limited duration of action in motoric and sensoric. This research aimed to provide an overview on the effect of adding clonidine 75 mcg to 12.5 mg 0.5% levobupivacaine on the motoric and sensoric blockade action duration in lower extremity orthopedic surgery spinal anesthesia. This experimental prospective research used double blind randomized controlled trial approach on 36 patients with ASA I-II physical status who underwent lower extremity orthopedic surgery using spinal anesthesia in Dr. Hasan Sadikin General Hospital during the period of June to August 2014. LC group, clonidine 75 mcg was added to 12.5 mg 0.5% levobupivacaine. On LS group, 12.5 mg 0.5% mg levobupivacaine mixed with 0.5 mL 0.9% NaCl. The data were then statistically tested using t-test, Mann-Whitney, and chi-square. The result showed that the duration of action of sensoric blockade in LK group was significantly longer, i.e. 224.44 (37.84) minutes compared to LS group, i.e. 107.89 (17.63) minutes (p=0.000). Duration of action of motoric blockade in LK group was significantly longer, i.e. 278,72 (41,75) minutes, compared to LS group, i.e. 128.39 (18.26) minutes (p=0.000). It is concluded that the additiona of clonidine 75 mcg to 12,5 mg 0,5% levobupivacaine significantly prolongs the duration of action of the motoric and sensoric blockade if given intrathecally. |
| first_indexed | 2024-04-11T23:41:23Z |
| format | Article |
| id | doaj.art-be08fb91180844a7ab751b88431c8e06 |
| institution | Directory Open Access Journal |
| issn | 2337-7909 2338-8463 |
| language | Indonesian |
| last_indexed | 2024-04-11T23:41:23Z |
| publishDate | 2015-04-01 |
| publisher | Universitas Padjadjaran |
| record_format | Article |
| series | Jurnal Anestesi Perioperatif |
| spelling | doaj.art-be08fb91180844a7ab751b88431c8e062022-12-22T03:56:46ZindUniversitas PadjadjaranJurnal Anestesi Perioperatif2337-79092338-84632015-04-013171310.15851/jap.v3n1.374Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas BawahFadlyansyah Ramli0Doddy Tavianto1Tinni T. Maskoen2Instalasi Anestesi dan Rawat Intensif Rumah Sakit Islam Fatimah CilacapDepartemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran Rumah Sakit Dr. Hasan Sadikin BandungDepartemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran Rumah Sakit Dr. Hasan Sadikin BandungSpinal anesthesia has some limitations that limits its use, such as limited duration of action in motoric and sensoric. This research aimed to provide an overview on the effect of adding clonidine 75 mcg to 12.5 mg 0.5% levobupivacaine on the motoric and sensoric blockade action duration in lower extremity orthopedic surgery spinal anesthesia. This experimental prospective research used double blind randomized controlled trial approach on 36 patients with ASA I-II physical status who underwent lower extremity orthopedic surgery using spinal anesthesia in Dr. Hasan Sadikin General Hospital during the period of June to August 2014. LC group, clonidine 75 mcg was added to 12.5 mg 0.5% levobupivacaine. On LS group, 12.5 mg 0.5% mg levobupivacaine mixed with 0.5 mL 0.9% NaCl. The data were then statistically tested using t-test, Mann-Whitney, and chi-square. The result showed that the duration of action of sensoric blockade in LK group was significantly longer, i.e. 224.44 (37.84) minutes compared to LS group, i.e. 107.89 (17.63) minutes (p=0.000). Duration of action of motoric blockade in LK group was significantly longer, i.e. 278,72 (41,75) minutes, compared to LS group, i.e. 128.39 (18.26) minutes (p=0.000). It is concluded that the additiona of clonidine 75 mcg to 12,5 mg 0,5% levobupivacaine significantly prolongs the duration of action of the motoric and sensoric blockade if given intrathecally.http://journal.fk.unpad.ac.id/index.php/jap/article/view/374 |
| spellingShingle | Fadlyansyah Ramli Doddy Tavianto Tinni T. Maskoen Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah Jurnal Anestesi Perioperatif |
| title | Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah |
| title_full | Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah |
| title_fullStr | Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah |
| title_full_unstemmed | Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah |
| title_short | Pengaruh Penambahan Klonidin 75 mcg pada 12,5 mg Levobupivakain 0,5% Secara Intratekal terhadap Lama Kerja Blokade Sensorik dan Motorik untuk Bedah Ortopedi Ekstremitas Bawah |
| title_sort | pengaruh penambahan klonidin 75 mcg pada 12 5 mg levobupivakain 0 5 secara intratekal terhadap lama kerja blokade sensorik dan motorik untuk bedah ortopedi ekstremitas bawah |
| url | http://journal.fk.unpad.ac.id/index.php/jap/article/view/374 |
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