Better prognosis of patients with glioma expressing FGF2-dependent PDGFRA irrespective of morphological diagnosis.
Signaling of platelet derived growth factor receptor alpha (PDGFRA) is critically involved in the development of gliomas. However, the clinical relevance of PDGFRA expression in glioma subtypes and the mechanisms of PDGFRA expression in gliomas have been controversial. Under the supervision of morph...
Main Authors: | Dongfeng Chen, Annette Persson, Yingyu Sun, Leif G Salford, David Gisselsson Nord, Elisabet Englund, Tao Jiang, Xiaolong Fan |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3632602?pdf=render |
Similar Items
-
Glioma cell proliferation controlled by ERK activity-dependent surface expression of PDGFRA.
by: Dongfeng Chen, et al.
Published: (2014-01-01) -
Glial progenitor-like phenotype in low-grade glioma and enhanced CD133-expression and neuronal lineage differentiation potential in high-grade glioma.
by: Johan Rebetz, et al.
Published: (2008-04-01) -
Morphological Correlates of KIT and PDGFRA Genotypes in Gastrointestinal Stromal Tumour
by: Valli PRIYA, et al.
Published: (2020-05-01) -
CDK4/6 and PDGFRA Signaling as Therapeutic Targets in Diffuse Intrinsic Pontine Glioma
by: Christine Hoeman, et al.
Published: (2018-05-01) -
Neomorphic PDGFRA extracellular domain driver mutations are resistant to PDGFRA targeted therapies
by: Carman K. M. Ip, et al.
Published: (2018-11-01)