Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation

Dl-3-n-Butylphthalide Exerts Dopaminergic Neuroprotection Through Inhibition of Neuroinflammation

Microglia-mediated neuroinflammation contributes to multiple neurodegenerative disorders, including PD. Therefore, the regulation of microglial activation probably has the therapeutic potential. This study is aimed to determine whether NBP could suppress microglial activation and protect dopaminergi...

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Bibliographic Details
Main Authors: Yajing Chen, Tingting Wu, Heng Li, Xuan Li, Qing Li, Xiaoying Zhu, Mei Yu, Sheng-Han Kuo, Fang Huang, Yun-Cheng Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Aging Neuroscience
Subjects:
dl-3-n-butylphthalide
MAPK
microglia
neuroinflammation
NF-κB
Parkinson’s disease
Online Access:https://www.frontiersin.org/article/10.3389/fnagi.2019.00044/full

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