Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus

Plasmids are major agents in the spread of antibiotic resistance genes among bacteria. How plasmids and their hosts coevolve to reduce the fitness cost associated with plasmid carriage when bacteria grow in an antibiotic-free environment is not well understood.

Bibliographic Details
Main Authors: Pedro Dorado-Morales, M. Pilar Garcillán-Barcia, Iñigo Lasa, Cristina Solano
Format: Article
Language:English
Published: American Society for Microbiology 2021-02-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.03094-20
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author Pedro Dorado-Morales
M. Pilar Garcillán-Barcia
Iñigo Lasa
Cristina Solano
author_facet Pedro Dorado-Morales
M. Pilar Garcillán-Barcia
Iñigo Lasa
Cristina Solano
author_sort Pedro Dorado-Morales
collection DOAJ
description Plasmids are major agents in the spread of antibiotic resistance genes among bacteria. How plasmids and their hosts coevolve to reduce the fitness cost associated with plasmid carriage when bacteria grow in an antibiotic-free environment is not well understood.
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spelling doaj.art-be10b8d9b2144a468c53979fc93934122022-12-21T21:09:40ZengAmerican Society for MicrobiologymBio2161-21292150-75112021-02-0112110.1128/mBio.03094-20Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureusPedro Dorado-Morales0M. Pilar Garcillán-Barcia1Iñigo Lasa2https://orcid.org/0000-0002-6625-9221Cristina Solano3https://orcid.org/0000-0002-6207-1766Laboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, SpainInstituto de Biomedicina y Biotecnología de Cantabria, Universidad de Cantabria—Consejo Superior de Investigaciones Científicas, Santander, Cantabria, SpainLaboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, SpainLaboratory of Microbial Pathogenesis, Navarrabiomed–Universidad Pública de Navarra–Complejo Hospitalario de Navarra, Instituto de Investigacion Sanitaria de Navarra, Pamplona, Navarra, SpainPlasmids are major agents in the spread of antibiotic resistance genes among bacteria. How plasmids and their hosts coevolve to reduce the fitness cost associated with plasmid carriage when bacteria grow in an antibiotic-free environment is not well understood.https://journals.asm.org/doi/10.1128/mBio.03094-20
spellingShingle Pedro Dorado-Morales
M. Pilar Garcillán-Barcia
Iñigo Lasa
Cristina Solano
Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
mBio
title Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
title_full Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
title_fullStr Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
title_full_unstemmed Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
title_short Fitness Cost Evolution of Natural Plasmids of Staphylococcus aureus
title_sort fitness cost evolution of natural plasmids of staphylococcus aureus
url https://journals.asm.org/doi/10.1128/mBio.03094-20
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