Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance

Diabetes is one of the most significant causes of death all over the world. This illness, due to abnormal blood glucose levels, leads to impaired wound healing and, as a result, foot ulcers. These ulcers cannot heal quickly in diabetic patients and may finally result in amputation. In recent years,...

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Main Authors: Azadeh Barjasteh, Neha Kaushik, Eun Ha Choi, Nagendra Kumar Kaushik
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/24/23/16657
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author Azadeh Barjasteh
Neha Kaushik
Eun Ha Choi
Nagendra Kumar Kaushik
author_facet Azadeh Barjasteh
Neha Kaushik
Eun Ha Choi
Nagendra Kumar Kaushik
author_sort Azadeh Barjasteh
collection DOAJ
description Diabetes is one of the most significant causes of death all over the world. This illness, due to abnormal blood glucose levels, leads to impaired wound healing and, as a result, foot ulcers. These ulcers cannot heal quickly in diabetic patients and may finally result in amputation. In recent years, different research has been conducted to heal diabetic foot ulcers: one of them is using cold atmospheric pressure plasma. Nowadays, cold atmospheric pressure plasma is highly regarded in medicine because of its positive effects and lack of side effects. These conditions have caused plasma to be considered a promising technology in medicine and especially diabetic wound healing because studies show that it can heal chronic wounds that are resistant to standard treatments. The positive effects of plasma are due to different reactive species, UV radiation, and electromagnetic fields. This work reviews ongoing cold atmospheric pressure plasma improvements in diabetic wound healing. It shows that plasma can be a promising tool in treating chronic wounds, including ones resulting from diabetes.
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spelling doaj.art-be10f1ef3bfb4a83a83e821d5912cf0f2023-12-08T15:16:40ZengMDPI AGInternational Journal of Molecular Sciences1661-65961422-00672023-11-0124231665710.3390/ijms242316657Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical SignificanceAzadeh Barjasteh0Neha Kaushik1Eun Ha Choi2Nagendra Kumar Kaushik3Department of Physics, Lorestan University, Khorramabad 68151-44316, IranDepartment of Biotechnology, College of Engineering, The University of Suwon, Hwaseong 18323, Republic of KoreaDepartment of Electrical and Biological Physics/Plasma, Bioscience Research Center, Kwangwoon University, Seoul 01897, Republic of KoreaDepartment of Electrical and Biological Physics/Plasma, Bioscience Research Center, Kwangwoon University, Seoul 01897, Republic of KoreaDiabetes is one of the most significant causes of death all over the world. This illness, due to abnormal blood glucose levels, leads to impaired wound healing and, as a result, foot ulcers. These ulcers cannot heal quickly in diabetic patients and may finally result in amputation. In recent years, different research has been conducted to heal diabetic foot ulcers: one of them is using cold atmospheric pressure plasma. Nowadays, cold atmospheric pressure plasma is highly regarded in medicine because of its positive effects and lack of side effects. These conditions have caused plasma to be considered a promising technology in medicine and especially diabetic wound healing because studies show that it can heal chronic wounds that are resistant to standard treatments. The positive effects of plasma are due to different reactive species, UV radiation, and electromagnetic fields. This work reviews ongoing cold atmospheric pressure plasma improvements in diabetic wound healing. It shows that plasma can be a promising tool in treating chronic wounds, including ones resulting from diabetes.https://www.mdpi.com/1422-0067/24/23/16657cold atmospheric plasmawound healingdiabetic wounds
spellingShingle Azadeh Barjasteh
Neha Kaushik
Eun Ha Choi
Nagendra Kumar Kaushik
Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance
International Journal of Molecular Sciences
cold atmospheric plasma
wound healing
diabetic wounds
title Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance
title_full Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance
title_fullStr Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance
title_full_unstemmed Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance
title_short Cold Atmospheric Pressure Plasma: A Growing Paradigm in Diabetic Wound Healing—Mechanism and Clinical Significance
title_sort cold atmospheric pressure plasma a growing paradigm in diabetic wound healing mechanism and clinical significance
topic cold atmospheric plasma
wound healing
diabetic wounds
url https://www.mdpi.com/1422-0067/24/23/16657
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AT eunhachoi coldatmosphericpressureplasmaagrowingparadigmindiabeticwoundhealingmechanismandclinicalsignificance
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