Paving the way to improve therapy for Myeloproliferative Neoplasms
Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that media...
Main Authors: | , |
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Format: | Article |
Language: | English |
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Nature Portfolio
2022-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-022-32694-2 |
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author | Megan Bywater Steven W. Lane |
author_facet | Megan Bywater Steven W. Lane |
author_sort | Megan Bywater |
collection | DOAJ |
description | Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that mediate treatment resistance. |
first_indexed | 2024-04-11T14:24:51Z |
format | Article |
id | doaj.art-be1b1db34a5f44258ba18302c97b57cc |
institution | Directory Open Access Journal |
issn | 2041-1723 |
language | English |
last_indexed | 2024-04-11T14:24:51Z |
publishDate | 2022-08-01 |
publisher | Nature Portfolio |
record_format | Article |
series | Nature Communications |
spelling | doaj.art-be1b1db34a5f44258ba18302c97b57cc2022-12-22T04:18:55ZengNature PortfolioNature Communications2041-17232022-08-011311310.1038/s41467-022-32694-2Paving the way to improve therapy for Myeloproliferative NeoplasmsMegan Bywater0Steven W. Lane1Cancer Program, QIMR Berghofer MRICancer Program, QIMR Berghofer MRILong-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that mediate treatment resistance.https://doi.org/10.1038/s41467-022-32694-2 |
spellingShingle | Megan Bywater Steven W. Lane Paving the way to improve therapy for Myeloproliferative Neoplasms Nature Communications |
title | Paving the way to improve therapy for Myeloproliferative Neoplasms |
title_full | Paving the way to improve therapy for Myeloproliferative Neoplasms |
title_fullStr | Paving the way to improve therapy for Myeloproliferative Neoplasms |
title_full_unstemmed | Paving the way to improve therapy for Myeloproliferative Neoplasms |
title_short | Paving the way to improve therapy for Myeloproliferative Neoplasms |
title_sort | paving the way to improve therapy for myeloproliferative neoplasms |
url | https://doi.org/10.1038/s41467-022-32694-2 |
work_keys_str_mv | AT meganbywater pavingthewaytoimprovetherapyformyeloproliferativeneoplasms AT stevenwlane pavingthewaytoimprovetherapyformyeloproliferativeneoplasms |