Paving the way to improve therapy for Myeloproliferative Neoplasms

Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that media...

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Main Authors: Megan Bywater, Steven W. Lane
Format: Article
Language:English
Published: Nature Portfolio 2022-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-32694-2
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author Megan Bywater
Steven W. Lane
author_facet Megan Bywater
Steven W. Lane
author_sort Megan Bywater
collection DOAJ
description Long-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that mediate treatment resistance.
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spelling doaj.art-be1b1db34a5f44258ba18302c97b57cc2022-12-22T04:18:55ZengNature PortfolioNature Communications2041-17232022-08-011311310.1038/s41467-022-32694-2Paving the way to improve therapy for Myeloproliferative NeoplasmsMegan Bywater0Steven W. Lane1Cancer Program, QIMR Berghofer MRICancer Program, QIMR Berghofer MRILong-acting IFNα induces durable molecular responses in myeloproliferative neoplasms. Emerging studies, including Saleiro et al. recently published in Nature Communications, have identified promising candidates that may synergise with IFNα by targeting stem cell function or feedback loops that mediate treatment resistance.https://doi.org/10.1038/s41467-022-32694-2
spellingShingle Megan Bywater
Steven W. Lane
Paving the way to improve therapy for Myeloproliferative Neoplasms
Nature Communications
title Paving the way to improve therapy for Myeloproliferative Neoplasms
title_full Paving the way to improve therapy for Myeloproliferative Neoplasms
title_fullStr Paving the way to improve therapy for Myeloproliferative Neoplasms
title_full_unstemmed Paving the way to improve therapy for Myeloproliferative Neoplasms
title_short Paving the way to improve therapy for Myeloproliferative Neoplasms
title_sort paving the way to improve therapy for myeloproliferative neoplasms
url https://doi.org/10.1038/s41467-022-32694-2
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