Obesity pharmaceutical correction in metabolic syndrome patients

Very high prevalence of obesity and metabolic syndrome (MS) is well known. The need for early treatment start and more selective pharmaceutical treatment of MS has been noted in many publications. As pathogenetic therapy, numerous methods for body mass (BM) reduction have been proposed, due to well-...

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Main Authors: V. B. Mychka, I. E. Chazova, V. V. Gornostaev, V. B. Sergienko
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2005-08-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/991
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author V. B. Mychka
I. E. Chazova
V. V. Gornostaev
V. B. Sergienko
author_facet V. B. Mychka
I. E. Chazova
V. V. Gornostaev
V. B. Sergienko
author_sort V. B. Mychka
collection DOAJ
description Very high prevalence of obesity and metabolic syndrome (MS) is well known. The need for early treatment start and more selective pharmaceutical treatment of MS has been noted in many publications. As pathogenetic therapy, numerous methods for body mass (BM) reduction have been proposed, due to well-known prevalent role of obesity in MS pathogenesis. Because of various reasons, many medications haven’t achieved wide acceptance in clinical settings. The article summarizes the experience in BM reduction with an effective drug – orlistat (Xenical®). Based on the authentic authors’ data, beneficial effects of orlistat on carbohydrate and lipid metabolism, 24-hour blood pressure profile, and cerebral perfusion are demonstrated. The authors prove that orlistat is highly recommended for cardiovascular complication risk reduction in MS patients.
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spelling doaj.art-be1b2df7405c426b993f444a3b2979162023-03-13T07:23:11Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252005-08-01447984705Obesity pharmaceutical correction in metabolic syndrome patientsV. B. Mychka0I. E. Chazova1V. V. Gornostaev2V. B. Sergienko3Научно-исследовательский институт клинической кардиологии им. А.Л. Мясникова РКНПК Росздрава, МоскваНаучно-исследовательский институт клинической кардиологии им. А.Л. Мясникова РКНПК Росздрава, МоскваНаучно-исследовательский институт клинической кардиологии им. А.Л. Мясникова РКНПК Росздрава, МоскваНаучно-исследовательский институт клинической кардиологии им. А.Л. Мясникова РКНПК Росздрава, МоскваVery high prevalence of obesity and metabolic syndrome (MS) is well known. The need for early treatment start and more selective pharmaceutical treatment of MS has been noted in many publications. As pathogenetic therapy, numerous methods for body mass (BM) reduction have been proposed, due to well-known prevalent role of obesity in MS pathogenesis. Because of various reasons, many medications haven’t achieved wide acceptance in clinical settings. The article summarizes the experience in BM reduction with an effective drug – orlistat (Xenical®). Based on the authentic authors’ data, beneficial effects of orlistat on carbohydrate and lipid metabolism, 24-hour blood pressure profile, and cerebral perfusion are demonstrated. The authors prove that orlistat is highly recommended for cardiovascular complication risk reduction in MS patients.https://cardiovascular.elpub.ru/jour/article/view/991метаболический синдромартериальная гипертонияожирениемедикаментозное лечениеорлистат
spellingShingle V. B. Mychka
I. E. Chazova
V. V. Gornostaev
V. B. Sergienko
Obesity pharmaceutical correction in metabolic syndrome patients
Кардиоваскулярная терапия и профилактика
метаболический синдром
артериальная гипертония
ожирение
медикаментозное лечение
орлистат
title Obesity pharmaceutical correction in metabolic syndrome patients
title_full Obesity pharmaceutical correction in metabolic syndrome patients
title_fullStr Obesity pharmaceutical correction in metabolic syndrome patients
title_full_unstemmed Obesity pharmaceutical correction in metabolic syndrome patients
title_short Obesity pharmaceutical correction in metabolic syndrome patients
title_sort obesity pharmaceutical correction in metabolic syndrome patients
topic метаболический синдром
артериальная гипертония
ожирение
медикаментозное лечение
орлистат
url https://cardiovascular.elpub.ru/jour/article/view/991
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AT iechazova obesitypharmaceuticalcorrectioninmetabolicsyndromepatients
AT vvgornostaev obesitypharmaceuticalcorrectioninmetabolicsyndromepatients
AT vbsergienko obesitypharmaceuticalcorrectioninmetabolicsyndromepatients