Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant?
ObjectiveTo quantify fetal cardiovascular parameters utilizing fetal-specific 2D speckle tracking technique and to explore the differences in size and systolic function of the left and right ventricles in low-risk pregnancy.MethodsA prospective cohort study was performed in 453 low-risk single fetus...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-03-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1052178/full |
| _version_ | 1797868237189283840 |
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| author | Chen Zhu Man Li Cheng-Jie Xu Meng-Juan Ding Yu Xiong Rui Liu Yun-Yun Ren |
| author_facet | Chen Zhu Man Li Cheng-Jie Xu Meng-Juan Ding Yu Xiong Rui Liu Yun-Yun Ren |
| author_sort | Chen Zhu |
| collection | DOAJ |
| description | ObjectiveTo quantify fetal cardiovascular parameters utilizing fetal-specific 2D speckle tracking technique and to explore the differences in size and systolic function of the left and right ventricles in low-risk pregnancy.MethodsA prospective cohort study was performed in 453 low-risk single fetuses (28+0–39+6 weeks) to evaluate ventricular size [i.e., end-diastolic length (EDL), end-systolic length (ESL), end-diastolic diameter (ED), end-systolic diameter (ES), end-diastolic area, end-systolic area, end-diastolic volume (EDV), and end-systolic volume (ESV)] and systolic function [i.e., ejection fraction (EF), stroke volume (SV), cardiac output (CO), cardiac output per kilogram (CO/KG), and stroke volume per kilogram (SV/KG)].ResultsThis study showed that (1) the reproducibility of the interobserver and intraobserver measurements was good to excellent (ICC 0.626–0.936); (2) with advancing gestation, fetal ventricular size and systolic function increased, whereas right ventricular (RV) EF decreased and left ventricular (LV) EF was not significantly changed; (3) LV length was longer than RV length in diastole (2.24 vs. 1.96 cm, P < 0.001) and systole (1.72 vs. 1.52 cm, P < 0.001); (4) LV ED-S1 and ES-S1 were shorter than the RV ED-S1 and ES-S1 (12.87 vs. 13.43 mm, P < 0.001; 5.09 vs. 5.61 mm, P < 0.001); (5) there were no differences between the LV and RV in EDA or EDV; (6) the mean EDV ratio of right-to-left ventricle was 1.076 (95% CI, 1.038–1.114), and the mean ESV ratio was 1.628 (95% CI, 1.555–1.701); (7) the EF, CO and SV of the LV were greater than the RV (EF: 62.69% vs. 46.09%, P < 0.001; CO: 167.85 vs. 128.69 ml, P < 0.001; SV: 1.18 vs. 0.88 ml, P < 0.001); (8) SV and CO increased with ED-S1 and EDL, but EF was not significantly changed.ConclusionLow-risk fetal cardiovascular physiology is characterized by a larger RV volume (especially after 32 weeks) and greater LV outputs (EF, CO, SV, SV/KG and CO/KG). |
| first_indexed | 2024-04-09T23:53:54Z |
| format | Article |
| id | doaj.art-be1c1be75e044605a6f27d0fffc82ba5 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-04-09T23:53:54Z |
| publishDate | 2023-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-be1c1be75e044605a6f27d0fffc82ba52023-03-17T04:34:32ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2023-03-011010.3389/fcvm.2023.10521781052178Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant?Chen Zhu0Man Li1Cheng-Jie Xu2Meng-Juan Ding3Yu Xiong4Rui Liu5Yun-Yun Ren6Department of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Information Technology, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Obstetrics, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaDepartment of Ultrasound, Obstetrics and Gynecology Hospital of Fudan University, Shanghai, ChinaObjectiveTo quantify fetal cardiovascular parameters utilizing fetal-specific 2D speckle tracking technique and to explore the differences in size and systolic function of the left and right ventricles in low-risk pregnancy.MethodsA prospective cohort study was performed in 453 low-risk single fetuses (28+0–39+6 weeks) to evaluate ventricular size [i.e., end-diastolic length (EDL), end-systolic length (ESL), end-diastolic diameter (ED), end-systolic diameter (ES), end-diastolic area, end-systolic area, end-diastolic volume (EDV), and end-systolic volume (ESV)] and systolic function [i.e., ejection fraction (EF), stroke volume (SV), cardiac output (CO), cardiac output per kilogram (CO/KG), and stroke volume per kilogram (SV/KG)].ResultsThis study showed that (1) the reproducibility of the interobserver and intraobserver measurements was good to excellent (ICC 0.626–0.936); (2) with advancing gestation, fetal ventricular size and systolic function increased, whereas right ventricular (RV) EF decreased and left ventricular (LV) EF was not significantly changed; (3) LV length was longer than RV length in diastole (2.24 vs. 1.96 cm, P < 0.001) and systole (1.72 vs. 1.52 cm, P < 0.001); (4) LV ED-S1 and ES-S1 were shorter than the RV ED-S1 and ES-S1 (12.87 vs. 13.43 mm, P < 0.001; 5.09 vs. 5.61 mm, P < 0.001); (5) there were no differences between the LV and RV in EDA or EDV; (6) the mean EDV ratio of right-to-left ventricle was 1.076 (95% CI, 1.038–1.114), and the mean ESV ratio was 1.628 (95% CI, 1.555–1.701); (7) the EF, CO and SV of the LV were greater than the RV (EF: 62.69% vs. 46.09%, P < 0.001; CO: 167.85 vs. 128.69 ml, P < 0.001; SV: 1.18 vs. 0.88 ml, P < 0.001); (8) SV and CO increased with ED-S1 and EDL, but EF was not significantly changed.ConclusionLow-risk fetal cardiovascular physiology is characterized by a larger RV volume (especially after 32 weeks) and greater LV outputs (EF, CO, SV, SV/KG and CO/KG).https://www.frontiersin.org/articles/10.3389/fcvm.2023.1052178/fullfetal echocardiographyfetal heartultrasoundspeckle trackingfetalHQventricular size |
| spellingShingle | Chen Zhu Man Li Cheng-Jie Xu Meng-Juan Ding Yu Xiong Rui Liu Yun-Yun Ren Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant? Frontiers in Cardiovascular Medicine fetal echocardiography fetal heart ultrasound speckle tracking fetalHQ ventricular size |
| title | Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant? |
| title_full | Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant? |
| title_fullStr | Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant? |
| title_full_unstemmed | Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant? |
| title_short | Comparison of the left and right ventricular size and systolic function of low-risk fetuses in the third trimester: Which is more dominant? |
| title_sort | comparison of the left and right ventricular size and systolic function of low risk fetuses in the third trimester which is more dominant |
| topic | fetal echocardiography fetal heart ultrasound speckle tracking fetalHQ ventricular size |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2023.1052178/full |
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