Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels

Vesicular Glutamate Transporters (SLCA17 A6, 7, 8) Control Synaptic Phosphate Levels

Summary: Vesicular glutamate transporters (VGLUTs) fill synaptic vesicles with glutamate. VGLUTs were originally identified as sodium-dependent transporters of inorganic phosphate (Pi), but the physiological relevance of this activity remains unclear. Heterologous expression of all three VGLUTs grea...

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Bibliographic Details
Main Authors: Cyril Cheret, Marcelo Ganzella, Julia Preobraschenski, Reinhard Jahn, Gudrun Ahnert-Hilger
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Cell Reports
Subjects:
VGLUTs
phosphate
glutamate
Na+-dependent transport
substrate binding site
Pi homeostasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720316120

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