Natural Course of Activated Phosphoinositide 3-Kinase Delta Syndrome in Childhood and Adolescence
Activated phosphoinositide 3-kinase delta syndrome (APDS), caused by mutations in PI3Kδ catalytic p110δ (PIK3CD) or regulatory p85α (PIK3R1) subunits, is a primary immunodeficiency affecting both humoral and cellular immunity, which shares some phenotypic similarities with hyper-IgM syndromes and co...
| Автори: | , , , , , |
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| Формат: | Стаття |
| Мова: | English |
| Опубліковано: |
Frontiers Media S.A.
2021-07-01
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| Серія: | Frontiers in Pediatrics |
| Предмети: | |
| Онлайн доступ: | https://www.frontiersin.org/articles/10.3389/fped.2021.697706/full |