Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.

The methanol extract of leaves of Kydia calycina Roxb. was screened for the analgesic (using hot plate test and acetic acid-induced writhing test in mice) and anti-inflammatory (using rat paw edema test) activity at the doses of 200 and 400 mg/kg body weight. A significant (p<0.0005) analgesic ef...

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Main Author: Baburao Bhukya, Rama Narsimha Reddy Anreddy, Carey M. William and Krishna Mohan Gottumukkala
Format: Article
Language:English
Published: Bangladesh Pharmacological Society 2009-12-01
Series:Bangladesh Journal of Pharmacology
Subjects:
Online Access:http://www.banglajol.info/index.php/BJP/article/download/2112/2150
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author Baburao Bhukya, Rama Narsimha Reddy Anreddy, Carey M. William and Krishna Mohan Gottumukkala
author_facet Baburao Bhukya, Rama Narsimha Reddy Anreddy, Carey M. William and Krishna Mohan Gottumukkala
author_sort Baburao Bhukya, Rama Narsimha Reddy Anreddy, Carey M. William and Krishna Mohan Gottumukkala
collection DOAJ
description The methanol extract of leaves of Kydia calycina Roxb. was screened for the analgesic (using hot plate test and acetic acid-induced writhing test in mice) and anti-inflammatory (using rat paw edema test) activity at the doses of 200 and 400 mg/kg body weight. A significant (p<0.0005) analgesic effect was observed with 200 mg/kg and 400 mg/kg in both tests. The maximum anti-inflammatory response was produced at 3 hour with extract doses of 200 and 400 mg/kg. These results suggest that the methanol extract of K. calycina has exhibited significant analgesic and anti-inflammatory effects, which were comparable with standard drugs.
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spelling doaj.art-be261060ac924fa69c49118434bedc282022-12-22T02:48:22ZengBangladesh Pharmacological SocietyBangladesh Journal of Pharmacology1991-007X1991-00882009-12-0142101104Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.Baburao Bhukya, Rama Narsimha Reddy Anreddy, Carey M. William and Krishna Mohan GottumukkalaThe methanol extract of leaves of Kydia calycina Roxb. was screened for the analgesic (using hot plate test and acetic acid-induced writhing test in mice) and anti-inflammatory (using rat paw edema test) activity at the doses of 200 and 400 mg/kg body weight. A significant (p<0.0005) analgesic effect was observed with 200 mg/kg and 400 mg/kg in both tests. The maximum anti-inflammatory response was produced at 3 hour with extract doses of 200 and 400 mg/kg. These results suggest that the methanol extract of K. calycina has exhibited significant analgesic and anti-inflammatory effects, which were comparable with standard drugs.www.banglajol.info/index.php/BJP/article/download/2112/2150AnalgesicAnti-inflammatoryCarrageenanKydia calycina
spellingShingle Baburao Bhukya, Rama Narsimha Reddy Anreddy, Carey M. William and Krishna Mohan Gottumukkala
Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.
Bangladesh Journal of Pharmacology
Analgesic
Anti-inflammatory
Carrageenan
Kydia calycina
title Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.
title_full Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.
title_fullStr Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.
title_full_unstemmed Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.
title_short Analgesic and anti-inflammatory activities of leaf extract of Kydia calycina Roxb.
title_sort analgesic and anti inflammatory activities of leaf extract of kydia calycina roxb
topic Analgesic
Anti-inflammatory
Carrageenan
Kydia calycina
url http://www.banglajol.info/index.php/BJP/article/download/2112/2150
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