Ichthyosis Uteri Associated with Endometrial Adenocarcinoma: A Case Report
The replacement of the entire or extensive parts of endometrial lining by stratified squamous epithelium is a rare entity known as ichthyosis uteri. It is considered to be a benign condition but may be associated with dysplastic changes and primary squamous cell carcinoma of the endometrium. Its a...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
JCDR Research and Publications Private Limited
2017-06-01
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| Series: | Journal of Clinical and Diagnostic Research |
| Subjects: | |
| Online Access: | https://jcdr.net/articles/PDF/10116/27951_CE[Ra1]_F(RK)_PF1(PG_RK)_PFA(NC).pdf |
| Summary: | The replacement of the entire or extensive parts of endometrial lining by stratified squamous epithelium is a rare entity known as ichthyosis
uteri. It is considered to be a benign condition but may be associated with dysplastic changes and primary squamous cell carcinoma of
the endometrium. Its association with endometrial adenocarcinoma is very rare. The aetiology of this condition is not clearly understood
till date. We report a case of ichthyosis uteri associated with endometrial adenocarcinoma in a 70-year-old female who presented with
complaint of per-vaginal bleeding for six months and underwent hysterectomy after being diagnosed with endometrial carcinoma.
Microscopic examination of sections revealed endometrioid adenocarcinoma International Federation of Gynaecology and Obstetrics
(FIGO) Grade 3 along with extensive replacement of the endometrial lining by stratified squamous epithelium, consistent with ichthyosis
uteri. Although ichthyosis uteri is considered benign and its malignant potential is yet to be established, its association with endometrial
malignancies, both squamous and adenocarcinoma, necessitates extensive sampling of the uterus if any focus of squamous metaplasia
is identified in a hysterectomy specimen, to rule out a co-existing carcinoma. |
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| ISSN: | 2249-782X 0973-709X |