Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan
<p>Abstract</p> <p>Background</p> <p>To investigate the relationship between soy consumption, COPD risk and the prevalence of respiratory symptoms, a case-control study was conducted in Japan.</p> <p>Methods</p> <p>A total of 278 eligible patient...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2009-06-01
|
| Series: | Respiratory Research |
| Online Access: | http://respiratory-research.com/content/10/1/56 |
| _version_ | 1811297334087122944 |
|---|---|
| author | Tanikawa Yoshimasa Hiramatsu Tetsuo Zhao Yun Binns Colin W Lee Andy H Hirayama Fumi Nishimura Koichi Taniguchi Hiroyuki |
| author_facet | Tanikawa Yoshimasa Hiramatsu Tetsuo Zhao Yun Binns Colin W Lee Andy H Hirayama Fumi Nishimura Koichi Taniguchi Hiroyuki |
| author_sort | Tanikawa Yoshimasa |
| collection | DOAJ |
| description | <p>Abstract</p> <p>Background</p> <p>To investigate the relationship between soy consumption, COPD risk and the prevalence of respiratory symptoms, a case-control study was conducted in Japan.</p> <p>Methods</p> <p>A total of 278 eligible patients (244 men and 34 women), aged 50–75 years with COPD diagnosed within the past four years, were referred by respiratory physicians, while 340 controls (272 men and 68 women) were recruited from the community. All participants underwent spirometric measurements of respiratory function. Information on demographics, lifestyle characteristics and habitual food consumption was obtained using a structured questionnaire.</p> <p>Results</p> <p>Total soy consumption was positively correlated with observed lung function measures. The mean soy intake was significantly higher among controls (59.98, SD 50.23 g/day) than cases (44.84, SD 28.5 g/day). A significant reduction in COPD risk was evident for highest versus lowest quartile of daily intake of total soybean products, with adjusted odds ratio (OR) 0.392, 95% CI 0.194–0.793, <it>p </it>for trend 0.001. Similar decreases in COPD risk were associated with frequent and higher intake of soy foods such as tofu and bean sprouts, whereas respiratory symptoms were inversely associated with high consumption of soy foods, especially for breathlessness (OR 0.989, 95% CI 0.982–0.996).</p> <p>Conclusion</p> <p>Increasing soy consumption was associated with a decreased risk of COPD and breathlessness.</p> |
| first_indexed | 2024-04-13T06:01:47Z |
| format | Article |
| id | doaj.art-be27b5fa548b48e390ee069eda55b285 |
| institution | Directory Open Access Journal |
| issn | 1465-9921 |
| language | English |
| last_indexed | 2024-04-13T06:01:47Z |
| publishDate | 2009-06-01 |
| publisher | BMC |
| record_format | Article |
| series | Respiratory Research |
| spelling | doaj.art-be27b5fa548b48e390ee069eda55b2852022-12-22T02:59:24ZengBMCRespiratory Research1465-99212009-06-011015610.1186/1465-9921-10-56Soy consumption and risk of COPD and respiratory symptoms: a case-control study in JapanTanikawa YoshimasaHiramatsu TetsuoZhao YunBinns Colin WLee Andy HHirayama FumiNishimura KoichiTaniguchi Hiroyuki<p>Abstract</p> <p>Background</p> <p>To investigate the relationship between soy consumption, COPD risk and the prevalence of respiratory symptoms, a case-control study was conducted in Japan.</p> <p>Methods</p> <p>A total of 278 eligible patients (244 men and 34 women), aged 50–75 years with COPD diagnosed within the past four years, were referred by respiratory physicians, while 340 controls (272 men and 68 women) were recruited from the community. All participants underwent spirometric measurements of respiratory function. Information on demographics, lifestyle characteristics and habitual food consumption was obtained using a structured questionnaire.</p> <p>Results</p> <p>Total soy consumption was positively correlated with observed lung function measures. The mean soy intake was significantly higher among controls (59.98, SD 50.23 g/day) than cases (44.84, SD 28.5 g/day). A significant reduction in COPD risk was evident for highest versus lowest quartile of daily intake of total soybean products, with adjusted odds ratio (OR) 0.392, 95% CI 0.194–0.793, <it>p </it>for trend 0.001. Similar decreases in COPD risk were associated with frequent and higher intake of soy foods such as tofu and bean sprouts, whereas respiratory symptoms were inversely associated with high consumption of soy foods, especially for breathlessness (OR 0.989, 95% CI 0.982–0.996).</p> <p>Conclusion</p> <p>Increasing soy consumption was associated with a decreased risk of COPD and breathlessness.</p>http://respiratory-research.com/content/10/1/56 |
| spellingShingle | Tanikawa Yoshimasa Hiramatsu Tetsuo Zhao Yun Binns Colin W Lee Andy H Hirayama Fumi Nishimura Koichi Taniguchi Hiroyuki Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan Respiratory Research |
| title | Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan |
| title_full | Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan |
| title_fullStr | Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan |
| title_full_unstemmed | Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan |
| title_short | Soy consumption and risk of COPD and respiratory symptoms: a case-control study in Japan |
| title_sort | soy consumption and risk of copd and respiratory symptoms a case control study in japan |
| url | http://respiratory-research.com/content/10/1/56 |
| work_keys_str_mv | AT tanikawayoshimasa soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT hiramatsutetsuo soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT zhaoyun soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT binnscolinw soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT leeandyh soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT hirayamafumi soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT nishimurakoichi soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan AT taniguchihiroyuki soyconsumptionandriskofcopdandrespiratorysymptomsacasecontrolstudyinjapan |