Evolution and Comprehensive Analysis of DNaseI Hypersensitive Sites in Regulatory Regions of Primate Brain-Related Genes

Evolution and Comprehensive Analysis of DNaseI Hypersensitive Sites in Regulatory Regions of Primate Brain-Related Genes

How the human brain differs from those of non-human primates is largely unknown and the complex drivers underlying such differences at the genomic level remain unclear. In this study, we selected 243 brain-related genes, based on Gene Ontology, and identified 184,113 DNaseI hypersensitive sites (DHS...

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Bibliographic Details
Main Authors: Yueer Lu, Xiao Wang, Hang Yu, Jianlin Li, Zhiqiang Jiang, Bangwei Chen, Yueqi Lu, Wei Wang, Chongyin Han, Ying Ouyang, Lizhen Huang, Chunbo Chen, Weidong Tian, Fei Ling
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Genetics
Subjects:
brain
regulatory region
DNaseI hypersensitive sites
evolution
primates
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.00152/full

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