Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains
Sleep spindles are thought to promote memory consolidation. Recently, we have shown that visuomotor adaptation (VMA) learning increases the density of spindles and promotes the coupling between spindles and slow oscillations, locally, with the level of spindle-SO synchrony predicting overnight memor...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Neuroscience |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fnins.2022.803387/full |
| _version_ | 1830413321626451968 |
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| author | Agustín Solano Luis A. Riquelme Daniel Perez-Chada Valeria Della-Maggiore |
| author_facet | Agustín Solano Luis A. Riquelme Daniel Perez-Chada Valeria Della-Maggiore |
| author_sort | Agustín Solano |
| collection | DOAJ |
| description | Sleep spindles are thought to promote memory consolidation. Recently, we have shown that visuomotor adaptation (VMA) learning increases the density of spindles and promotes the coupling between spindles and slow oscillations, locally, with the level of spindle-SO synchrony predicting overnight memory retention. Yet, growing evidence suggests that the rhythmicity in spindle occurrence may also influence the stabilization of declarative and procedural memories. Here, we examined if VMA learning promotes the temporal organization of sleep spindles into trains. We found that VMA increased the proportion of spindles and spindle-SO couplings in trains. In agreement with our previous work, this modulation was observed over the contralateral hemisphere to the trained hand, and predicted overnight memory retention. Interestingly, spindles grouped in a cluster showed greater amplitude and duration than isolated spindles. The fact that these features increased as a function of train length, provides evidence supporting a biological advantage of this temporal arrangement. Our work opens the possibility that the periodicity of NREM oscillations may be relevant in the stabilization of procedural memories. |
| first_indexed | 2024-12-20T20:24:06Z |
| format | Article |
| id | doaj.art-be2b234b154046bbab5428bd8eff55d0 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-12-20T20:24:06Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-be2b234b154046bbab5428bd8eff55d02022-12-21T19:27:30ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2022-03-011610.3389/fnins.2022.803387803387Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into TrainsAgustín Solano0Luis A. Riquelme1Daniel Perez-Chada2Valeria Della-Maggiore3IFIBIO Houssay, Department of Physiology, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaIFIBIO Houssay, Department of Physiology, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaDepartment of Internal Medicine, Pulmonary and Sleep Medicine Service, Austral University Hospital, Buenos Aires, ArgentinaIFIBIO Houssay, Department of Physiology, School of Medicine, University of Buenos Aires, Buenos Aires, ArgentinaSleep spindles are thought to promote memory consolidation. Recently, we have shown that visuomotor adaptation (VMA) learning increases the density of spindles and promotes the coupling between spindles and slow oscillations, locally, with the level of spindle-SO synchrony predicting overnight memory retention. Yet, growing evidence suggests that the rhythmicity in spindle occurrence may also influence the stabilization of declarative and procedural memories. Here, we examined if VMA learning promotes the temporal organization of sleep spindles into trains. We found that VMA increased the proportion of spindles and spindle-SO couplings in trains. In agreement with our previous work, this modulation was observed over the contralateral hemisphere to the trained hand, and predicted overnight memory retention. Interestingly, spindles grouped in a cluster showed greater amplitude and duration than isolated spindles. The fact that these features increased as a function of train length, provides evidence supporting a biological advantage of this temporal arrangement. Our work opens the possibility that the periodicity of NREM oscillations may be relevant in the stabilization of procedural memories.https://www.frontiersin.org/articles/10.3389/fnins.2022.803387/fullhumanmotor learningsleepspindle trainslow oscillation |
| spellingShingle | Agustín Solano Luis A. Riquelme Daniel Perez-Chada Valeria Della-Maggiore Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains Frontiers in Neuroscience human motor learning sleep spindle train slow oscillation |
| title | Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains |
| title_full | Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains |
| title_fullStr | Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains |
| title_full_unstemmed | Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains |
| title_short | Visuomotor Adaptation Modulates the Clustering of Sleep Spindles Into Trains |
| title_sort | visuomotor adaptation modulates the clustering of sleep spindles into trains |
| topic | human motor learning sleep spindle train slow oscillation |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2022.803387/full |
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