Role of FK506-sensitive signals in asthmatic lung inflammation

Role of FK506-sensitive signals in asthmatic lung inflammation

Asthma is airway inflammatory diseases caused by the activation of group 2 innate lymphoid cells (ILC2s) and type 2 helper T (TH2) cells. Cysteine proteases allergen cause tissue damage to airway epithelial cells and activate ILC2-mediated type 2 airway inflammation. FK506 is an immunosuppressive ag...

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Bibliographic Details
Main Authors:	Chihiro Tomiaki, Kosuke Miyauchi, Sewon Ki, Yoshie Suzuki, Narumi Suzuki, Hiroshi Morimoto, Yohei Mukoyama, Masato Kubo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-11-01
Series:	Frontiers in Immunology
Subjects:	asthma innate lymphocyte cells (ILCs) Th2 airway inflammation cytokines IL-13
Online Access:	https://www.frontiersin.org/articles/10.3389/fimmu.2022.1014462/full

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