Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome
Alexithymia is usually described by three main dimensions difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). The most commonly used questionnaire investigating alexithymia, the Toronto Alexithymia Scale (TAS-20), supports this three-f...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2020-04-01
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| Series: | Frontiers in Psychiatry |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00229/full |
| _version_ | 1818369335591174144 |
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| author | Alicia Fournier Alicia Fournier Laurie Mondillon Olivier Luminet Olivier Luminet Fréderic Canini Fréderic Canini Nicolas Mathieu Anne Sophie Gauchez Cécile Dantzer Bruno Bonaz Bruno Bonaz Sonia Pellissier |
| author_facet | Alicia Fournier Alicia Fournier Laurie Mondillon Olivier Luminet Olivier Luminet Fréderic Canini Fréderic Canini Nicolas Mathieu Anne Sophie Gauchez Cécile Dantzer Bruno Bonaz Bruno Bonaz Sonia Pellissier |
| author_sort | Alicia Fournier |
| collection | DOAJ |
| description | Alexithymia is usually described by three main dimensions difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). The most commonly used questionnaire investigating alexithymia, the Toronto Alexithymia Scale (TAS-20), supports this three-factor structure. One important assumption is that alexithymia severity is associated to vulnerability to somatic diseases, among them gastrointestinal disorders. However, the association between alexithymia and gastrointestinal disorders is not systematic, thus questioning the role of alexithymia as a vulnerability factor for those illnesses. A recent factor analysis suggested another four-factor structure for the TAS-20: difficulties in awareness of feelings (DAF), difficulties in interoceptive abilities (DIA), externally oriented thinking (EOT), and poor affective sharing (PAS). We assume that DIA and DAF might be more relevant to investigate the association between alexithymia and gastrointestinal disorders. The rationale is that DIA and DAF reflect impairments in emotion regulation that could contribute to an inappropriate autonomic and HPA axis homeostasis in irritable bowel syndrome (IBS), ulcerative colitis (UC), or Crohn’s disease (CD). The aim of this study was to investigate whether DIA and DAF are associated with the presence of IBS, UC or CD, while checking for anxiety, depression, parasympathetic (vagus nerve) activity and cortisol levels. We recruited control participants (n=26), and patients in remission who were diagnosed with IBS (n=24), UC (n=18), or CD (n=21). Participants completed questionnaires to assess anxiety, depression, and alexithymia. A blood sample and an electrocardiogram were used to measure the level of cortisol and parasympathetic activity, respectively. Logistic regressions with the four-factor structure of the TAS-20 revealed that DIA was a significant predictor of IBS (W(1)=6.27, p=.01). Conversely, DIA and DAF were not significant predictors in CD and UC patients. However, low cortisol level was a significant predictor of UC (W(1)=4.67, p=.035). Additional logistic regressions based on the original 3-factor structure of TAS-20 (DIF, DDF, and EOT) showed that only DDF was a significant predictor of CD [W(1)=6.16, p < .001]. The present study suggests that DIA is an important dimension for assessing potential risk for gastrointestinal diseases, in particular for IBS. |
| first_indexed | 2024-12-13T23:22:13Z |
| format | Article |
| id | doaj.art-be2ee3f0817f426196d23478696e098d |
| institution | Directory Open Access Journal |
| issn | 1664-0640 |
| language | English |
| last_indexed | 2024-12-13T23:22:13Z |
| publishDate | 2020-04-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Psychiatry |
| spelling | doaj.art-be2ee3f0817f426196d23478696e098d2022-12-21T23:27:41ZengFrontiers Media S.A.Frontiers in Psychiatry1664-06402020-04-011110.3389/fpsyt.2020.00229505451Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel SyndromeAlicia Fournier0Alicia Fournier1Laurie Mondillon2Olivier Luminet3Olivier Luminet4Fréderic Canini5Fréderic Canini6Nicolas Mathieu7Anne Sophie Gauchez8Cécile Dantzer9Bruno Bonaz10Bruno Bonaz11Sonia Pellissier12Université de Bourgogne, Laboratoire Psy-DREPI, Dijon, FranceMSHE Claude-Nicolas Ledoux, USR3124, Behaviors, Risk and Health, Besançon, FranceUniversité Clermont Auvergne, CNRS, Laboratoire de Psychologie Sociale et Cognitive, Team on Physiological and Psychosocial Stress, Well-being Physiological and Psychosocial Stress, Clermont-Ferrand, FranceResearch Institute for Psychological Sciences, Université catholique de Louvain, Louvain-La-Neuve, BelgiumFund for Scientific Research (FRS-FNRS), Brussels, BelgiumUnité de Neurophysiologie du Stress, Institut de Recherche Biomédicale des Armées (IRBA), Brétigny sur Orge, FranceÉcole du Val de Grâce, Paris, FranceService d’Hépato-Gastroentérology, Centre Hospitalier Universitaire de Grenoble, Grenoble, FranceInstitut de Biologie et Pathologie, Centre Hospitalier Universitaire de Grenoble, Grenoble, France0Université de Bordeaux, Laboratoire de Psychologie, Bordeaux, FranceService d’Hépato-Gastroentérology, Centre Hospitalier Universitaire de Grenoble, Grenoble, France1Université Grenoble Alpes, Grenoble Institute of Neurosciences, Grenoble, France2Université Savoie Mont Blanc, LIP/PC2S, Chambéry, FranceAlexithymia is usually described by three main dimensions difficulty identifying feelings (DIF), difficulty describing feelings (DDF), and externally oriented thinking (EOT). The most commonly used questionnaire investigating alexithymia, the Toronto Alexithymia Scale (TAS-20), supports this three-factor structure. One important assumption is that alexithymia severity is associated to vulnerability to somatic diseases, among them gastrointestinal disorders. However, the association between alexithymia and gastrointestinal disorders is not systematic, thus questioning the role of alexithymia as a vulnerability factor for those illnesses. A recent factor analysis suggested another four-factor structure for the TAS-20: difficulties in awareness of feelings (DAF), difficulties in interoceptive abilities (DIA), externally oriented thinking (EOT), and poor affective sharing (PAS). We assume that DIA and DAF might be more relevant to investigate the association between alexithymia and gastrointestinal disorders. The rationale is that DIA and DAF reflect impairments in emotion regulation that could contribute to an inappropriate autonomic and HPA axis homeostasis in irritable bowel syndrome (IBS), ulcerative colitis (UC), or Crohn’s disease (CD). The aim of this study was to investigate whether DIA and DAF are associated with the presence of IBS, UC or CD, while checking for anxiety, depression, parasympathetic (vagus nerve) activity and cortisol levels. We recruited control participants (n=26), and patients in remission who were diagnosed with IBS (n=24), UC (n=18), or CD (n=21). Participants completed questionnaires to assess anxiety, depression, and alexithymia. A blood sample and an electrocardiogram were used to measure the level of cortisol and parasympathetic activity, respectively. Logistic regressions with the four-factor structure of the TAS-20 revealed that DIA was a significant predictor of IBS (W(1)=6.27, p=.01). Conversely, DIA and DAF were not significant predictors in CD and UC patients. However, low cortisol level was a significant predictor of UC (W(1)=4.67, p=.035). Additional logistic regressions based on the original 3-factor structure of TAS-20 (DIF, DDF, and EOT) showed that only DDF was a significant predictor of CD [W(1)=6.16, p < .001]. The present study suggests that DIA is an important dimension for assessing potential risk for gastrointestinal diseases, in particular for IBS.https://www.frontiersin.org/article/10.3389/fpsyt.2020.00229/fullinflammatory bowel diseaseirritable bowel syndromealexithymiainteroceptive abilitieshypothalamic-pituitary adrenal axis |
| spellingShingle | Alicia Fournier Alicia Fournier Laurie Mondillon Olivier Luminet Olivier Luminet Fréderic Canini Fréderic Canini Nicolas Mathieu Anne Sophie Gauchez Cécile Dantzer Bruno Bonaz Bruno Bonaz Sonia Pellissier Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome Frontiers in Psychiatry inflammatory bowel disease irritable bowel syndrome alexithymia interoceptive abilities hypothalamic-pituitary adrenal axis |
| title | Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome |
| title_full | Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome |
| title_fullStr | Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome |
| title_full_unstemmed | Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome |
| title_short | Interoceptive Abilities in Inflammatory Bowel Diseases and Irritable Bowel Syndrome |
| title_sort | interoceptive abilities in inflammatory bowel diseases and irritable bowel syndrome |
| topic | inflammatory bowel disease irritable bowel syndrome alexithymia interoceptive abilities hypothalamic-pituitary adrenal axis |
| url | https://www.frontiersin.org/article/10.3389/fpsyt.2020.00229/full |
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