Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru

Abstract Objective To report an outbreak of ZIKV infection among asymptomatic pregnant women during 2016 in the city of Jaen, Cajamarca. Results Zika virus RNA was detected in 3.2% (n = 36) of cases by RT-PCR. The mean age of patients positive for ZIKV infection was 29.6 years. 7 patients (19.4%) in...

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Main Authors: Claudia Weilg, Lucinda Troyes, Zoila Villegas, Wilmer Silva-Caso, Fernando Mazulis, Ammy Febres, Mario Troyes, Miguel Angel Aguilar-Luis, Juana del Valle-Mendoza
Format: Article
Language:English
Published: BMC 2018-05-01
Series:BMC Research Notes
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13104-018-3400-z
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author Claudia Weilg
Lucinda Troyes
Zoila Villegas
Wilmer Silva-Caso
Fernando Mazulis
Ammy Febres
Mario Troyes
Miguel Angel Aguilar-Luis
Juana del Valle-Mendoza
author_facet Claudia Weilg
Lucinda Troyes
Zoila Villegas
Wilmer Silva-Caso
Fernando Mazulis
Ammy Febres
Mario Troyes
Miguel Angel Aguilar-Luis
Juana del Valle-Mendoza
author_sort Claudia Weilg
collection DOAJ
description Abstract Objective To report an outbreak of ZIKV infection among asymptomatic pregnant women during 2016 in the city of Jaen, Cajamarca. Results Zika virus RNA was detected in 3.2% (n = 36) of cases by RT-PCR. The mean age of patients positive for ZIKV infection was 29.6 years. 7 patients (19.4%) infected with ZIKV were in their first-trimester of gestation, 13 (36.1%) were in their second-trimester, and 16 (44%) were in their third-trimester. All of the infected pregnant women were asymptomatic. ZIKV infection remains a major public health issue that calls for constant epidemiological surveillance. It can cause the congenital Zika virus syndrome in the newborns of infected mothers. The lack of molecular diagnostic methods in isolated localities and the similarity of symptoms to other arboviral infections, lead to an under-diagnosis of this disease in endemic areas.
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spelling doaj.art-be319dfe832d4b8d99d246cbbb7be1602022-12-21T23:47:36ZengBMCBMC Research Notes1756-05002018-05-011111610.1186/s13104-018-3400-zDetection of Zika virus infection among asymptomatic pregnant women in the North of PeruClaudia Weilg0Lucinda Troyes1Zoila Villegas2Wilmer Silva-Caso3Fernando Mazulis4Ammy Febres5Mario Troyes6Miguel Angel Aguilar-Luis7Juana del Valle-Mendoza8School of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias AplicadasDirección Subregional de Salud de Jaén, Ministerio de SaludDirección Subregional de Salud de Jaén, Ministerio de SaludSchool of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias AplicadasSchool of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias AplicadasDirección Subregional de Salud de Jaén, Ministerio de SaludDirección Subregional de Salud de Jaén, Ministerio de SaludSchool of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias AplicadasSchool of Medicine, Research and Innovation Centre of the Faculty of Health Sciences, Universidad Peruana de Ciencias AplicadasAbstract Objective To report an outbreak of ZIKV infection among asymptomatic pregnant women during 2016 in the city of Jaen, Cajamarca. Results Zika virus RNA was detected in 3.2% (n = 36) of cases by RT-PCR. The mean age of patients positive for ZIKV infection was 29.6 years. 7 patients (19.4%) infected with ZIKV were in their first-trimester of gestation, 13 (36.1%) were in their second-trimester, and 16 (44%) were in their third-trimester. All of the infected pregnant women were asymptomatic. ZIKV infection remains a major public health issue that calls for constant epidemiological surveillance. It can cause the congenital Zika virus syndrome in the newborns of infected mothers. The lack of molecular diagnostic methods in isolated localities and the similarity of symptoms to other arboviral infections, lead to an under-diagnosis of this disease in endemic areas.http://link.springer.com/article/10.1186/s13104-018-3400-zZika virusPregnant womenOutbreak of ZikaPeru
spellingShingle Claudia Weilg
Lucinda Troyes
Zoila Villegas
Wilmer Silva-Caso
Fernando Mazulis
Ammy Febres
Mario Troyes
Miguel Angel Aguilar-Luis
Juana del Valle-Mendoza
Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru
BMC Research Notes
Zika virus
Pregnant women
Outbreak of Zika
Peru
title Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru
title_full Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru
title_fullStr Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru
title_full_unstemmed Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru
title_short Detection of Zika virus infection among asymptomatic pregnant women in the North of Peru
title_sort detection of zika virus infection among asymptomatic pregnant women in the north of peru
topic Zika virus
Pregnant women
Outbreak of Zika
Peru
url http://link.springer.com/article/10.1186/s13104-018-3400-z
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