Regulatory effects of intermittent noxious stimulation on spinal cord injury-sensitive microRNAs and their presumptive targets following spinal cord contusion

Regulatory effects of intermittent noxious stimulation on spinal cord injury-sensitive microRNAs and their presumptive targets following spinal cord contusion

Uncontrollable nociceptive stimulation adversely affects recovery in spinally contused rats. Spinal cord injury (SCI) results in altered microRNA (miRNA) expression both at, and distal to the lesion site. We hypothesized that uncontrollable nociception further influences SCI-sensitive miRNAs and a...

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Bibliographic Details
Main Authors: Eric R Strickland, Sarah A Woller, Sandra M Garraway, Michelle A Hook, James W Grau, Rajesh C Miranda
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-09-01
Series:Frontiers in Neural Circuits
Subjects:
Spinal Cord Injuries
microRNA
miR-1
mir-124
uncontrollable nociception
miR-129-2
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncir.2014.00117/full

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