Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2
The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in more than 16 million infections and more than 600,000 deaths worldwide. There is an urgent need to develop a safe and effective vaccine against SARS-CoV-2. Currently, several strategies are being pursued to...
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| Format: | Article |
| Language: | English |
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MDPI AG
2020-07-01
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| Series: | Pathogens |
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| Online Access: | https://www.mdpi.com/2076-0817/9/8/619 |
| _version_ | 1797561023089082368 |
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| author | Edris Shirvani Siba K. Samal |
| author_facet | Edris Shirvani Siba K. Samal |
| author_sort | Edris Shirvani |
| collection | DOAJ |
| description | The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in more than 16 million infections and more than 600,000 deaths worldwide. There is an urgent need to develop a safe and effective vaccine against SARS-CoV-2. Currently, several strategies are being pursued to develop a safe and effective SARS-CoV-2 vaccine. However, each vaccine strategy has distinct advantages and disadvantages. Therefore, it is important to evaluate multiple vaccine platforms to select the most efficient vaccine platform for SARS-CoV-2. In this regard, Newcastle disease virus (NDV), an avian virus, has several well-suited properties for development of a vector vaccine against SARS-CoV-2. Here, we elaborate on the idea of considering NDV as a vaccine vector for SARS-CoV-2. |
| first_indexed | 2024-03-10T18:08:28Z |
| format | Article |
| id | doaj.art-be331f4b4db7447b9ded5ac76f21b37f |
| institution | Directory Open Access Journal |
| issn | 2076-0817 |
| language | English |
| last_indexed | 2024-03-10T18:08:28Z |
| publishDate | 2020-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Pathogens |
| spelling | doaj.art-be331f4b4db7447b9ded5ac76f21b37f2023-11-20T08:21:13ZengMDPI AGPathogens2076-08172020-07-019861910.3390/pathogens9080619Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2Edris Shirvani0Siba K. Samal1Virginia-Maryland College of Veterinary Medicine, University of Maryland, College Park, MD 20742, USAVirginia-Maryland College of Veterinary Medicine, University of Maryland, College Park, MD 20742, USAThe emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in more than 16 million infections and more than 600,000 deaths worldwide. There is an urgent need to develop a safe and effective vaccine against SARS-CoV-2. Currently, several strategies are being pursued to develop a safe and effective SARS-CoV-2 vaccine. However, each vaccine strategy has distinct advantages and disadvantages. Therefore, it is important to evaluate multiple vaccine platforms to select the most efficient vaccine platform for SARS-CoV-2. In this regard, Newcastle disease virus (NDV), an avian virus, has several well-suited properties for development of a vector vaccine against SARS-CoV-2. Here, we elaborate on the idea of considering NDV as a vaccine vector for SARS-CoV-2.https://www.mdpi.com/2076-0817/9/8/619SARS-CoV-2COVID-19coronavirusNewcastle disease virus (NDV)vaccineviral vector and viral respiratory infection |
| spellingShingle | Edris Shirvani Siba K. Samal Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2 Pathogens SARS-CoV-2 COVID-19 coronavirus Newcastle disease virus (NDV) vaccine viral vector and viral respiratory infection |
| title | Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2 |
| title_full | Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2 |
| title_fullStr | Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2 |
| title_full_unstemmed | Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2 |
| title_short | Newcastle Disease Virus as a Vaccine Vector for SARS-CoV-2 |
| title_sort | newcastle disease virus as a vaccine vector for sars cov 2 |
| topic | SARS-CoV-2 COVID-19 coronavirus Newcastle disease virus (NDV) vaccine viral vector and viral respiratory infection |
| url | https://www.mdpi.com/2076-0817/9/8/619 |
| work_keys_str_mv | AT edrisshirvani newcastlediseasevirusasavaccinevectorforsarscov2 AT sibaksamal newcastlediseasevirusasavaccinevectorforsarscov2 |