Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum
Brain metastases from clear cell uterine carcinoma are extremely rare and are associated with a poor prognosis.Case report. A case of metastasis to the cerebellum in a 55-year-old patient with uterine adenocarcinoma is presented. The diagnosis of uterine cancer T2N1M1, stage IV was established in 20...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | Russian |
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Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)
2021-04-01
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| Series: | Сеченовский вестник |
| Subjects: | |
| Online Access: | https://www.sechenovmedj.com/jour/article/view/299 |
| _version_ | 1797873672741978112 |
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| author | N. V. Sevyan Yu. A. Tsybulskaya V. B. Karakhan A. Kh. Bekyashev E. V. Prozorenko |
| author_facet | N. V. Sevyan Yu. A. Tsybulskaya V. B. Karakhan A. Kh. Bekyashev E. V. Prozorenko |
| author_sort | N. V. Sevyan |
| collection | DOAJ |
| description | Brain metastases from clear cell uterine carcinoma are extremely rare and are associated with a poor prognosis.Case report. A case of metastasis to the cerebellum in a 55-year-old patient with uterine adenocarcinoma is presented. The diagnosis of uterine cancer T2N1M1, stage IV was established in 2016. Extirpation of the uterus, lymph node dissection, radiation and chemotherapy were performed. In 2018, the patient developed neurological symptoms. On MRI scan a tumor in the posterior cranial fossa was found. Without progression in other organs and the area of the primary focus. The tumor was resected. Histology: brain metastasis from clear cell uterine adenocarcinoma. Radiation and chemotherapy were performed. The patient’s neurological symptoms regressed. In the future, a complete response to the treatment was recorded.Discussion. Our case illustrates a rare metastasis from clear cell uterine adenocarcinoma. Brain metastases from uterine adenocarcinoma do not have a specific radiographic feature. Management of such patients should include a combined treatment, which can increase life expectancy. The life expectancy of our patient at the time of the control examination was 29 months. |
| first_indexed | 2024-04-10T01:19:58Z |
| format | Article |
| id | doaj.art-be3431f32fa049a5860c22e5003bcbbb |
| institution | Directory Open Access Journal |
| issn | 2218-7332 2658-3348 |
| language | Russian |
| last_indexed | 2024-04-10T01:19:58Z |
| publishDate | 2021-04-01 |
| publisher | Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) |
| record_format | Article |
| series | Сеченовский вестник |
| spelling | doaj.art-be3431f32fa049a5860c22e5003bcbbb2023-03-13T09:51:34ZrusFederal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University)Сеченовский вестник2218-73322658-33482021-04-01114434910.47093/2218-7332.2020.11.4.43-49163Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellumN. V. Sevyan0Yu. A. Tsybulskaya1V. B. Karakhan2A. Kh. Bekyashev3E. V. Prozorenko4Sechenov First Moscow State Medical University (Sechenov University); Blokhin National Medical Research Center of OncologySechenov First Moscow State Medical University (Sechenov University)Blokhin National Medical Research Center of OncologyBlokhin National Medical Research Center of OncologySechenov First Moscow State Medical University (Sechenov University); Blokhin National Medical Research Center of OncologyBrain metastases from clear cell uterine carcinoma are extremely rare and are associated with a poor prognosis.Case report. A case of metastasis to the cerebellum in a 55-year-old patient with uterine adenocarcinoma is presented. The diagnosis of uterine cancer T2N1M1, stage IV was established in 2016. Extirpation of the uterus, lymph node dissection, radiation and chemotherapy were performed. In 2018, the patient developed neurological symptoms. On MRI scan a tumor in the posterior cranial fossa was found. Without progression in other organs and the area of the primary focus. The tumor was resected. Histology: brain metastasis from clear cell uterine adenocarcinoma. Radiation and chemotherapy were performed. The patient’s neurological symptoms regressed. In the future, a complete response to the treatment was recorded.Discussion. Our case illustrates a rare metastasis from clear cell uterine adenocarcinoma. Brain metastases from uterine adenocarcinoma do not have a specific radiographic feature. Management of such patients should include a combined treatment, which can increase life expectancy. The life expectancy of our patient at the time of the control examination was 29 months.https://www.sechenovmedj.com/jour/article/view/299brain metastasisuterineclear cell adenocarcinomametastases to the cerebellumbrain |
| spellingShingle | N. V. Sevyan Yu. A. Tsybulskaya V. B. Karakhan A. Kh. Bekyashev E. V. Prozorenko Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum Сеченовский вестник brain metastasis uterine clear cell adenocarcinoma metastases to the cerebellum brain |
| title | Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum |
| title_full | Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum |
| title_fullStr | Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum |
| title_full_unstemmed | Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum |
| title_short | Metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum |
| title_sort | metastasis of clear cell adenocarcinoma of the uterine corpus to the cerebellum |
| topic | brain metastasis uterine clear cell adenocarcinoma metastases to the cerebellum brain |
| url | https://www.sechenovmedj.com/jour/article/view/299 |
| work_keys_str_mv | AT nvsevyan metastasisofclearcelladenocarcinomaoftheuterinecorpustothecerebellum AT yuatsybulskaya metastasisofclearcelladenocarcinomaoftheuterinecorpustothecerebellum AT vbkarakhan metastasisofclearcelladenocarcinomaoftheuterinecorpustothecerebellum AT akhbekyashev metastasisofclearcelladenocarcinomaoftheuterinecorpustothecerebellum AT evprozorenko metastasisofclearcelladenocarcinomaoftheuterinecorpustothecerebellum |