Case report: Durable response after pembrolizumab in combination with radiation - induced abscopal effect in platinum - refractory metastatic endometrial clear cell carcinoma

Case report: Durable response after pembrolizumab in combination with radiation - induced abscopal effect in platinum - refractory metastatic endometrial clear cell carcinoma

Advanced endometrial clear cell carcinoma (CCC) tends to have poor prognosis owing to aggressive clinical behavior and poor response to conventional chemotherapy. Herein, we report a case of platinum-refractory recurrent ECCC successfully treated with the combination of pembrolizumab, localized radi...

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Bibliographic Details
Main Authors: Chien-Hsiang Kao, Chien-Ting Liu, Hao Lin, Yung-Cheng Huang, Jui Lan, Yu-Che Ou, Hung-Chun Fu, Chen-Hsuan Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Immunology
Subjects:
endometrial cancer
abscopal effect
pembrolizumab
immunotherapy
clear cell carcinoma
ARID1A
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1079253/full

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