β-Catenin Is a Positive Regulator of Estrogen Receptor-α Function in Breast Cancer Cells

Estrogen receptor-alpha (ERα) is a key factor in the development of breast cancer in humans. The expression and activity of ERα is regulated by a multitude of intracellular and extracellular signals. Here we show a cross-talk between β-catenin and ERα in human breast cancer cells. Knockdown of β-cat...

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Bibliographic Details
Main Authors: Doris Mayer, Sina Grebhardt, Fee Schmitt, Nibedita Gupta
Format: Article
Language:English
Published: MDPI AG 2011-07-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/3/3/2990/